Dicloxacillin (sodium salt hydrate)

Dicloxacillin is a semisynthetic penicillin antibiotic that has activity against Gram-positive bacteria (MICs = 0.02-0.24 µg/ml for S. pyogenes, S. aureus, and D. pneumoniae). Dicloxacillin is protective against S. pyogenes, S. aureus, and D. pneumoniae infections in mice when administered subcutaneously or orally (PD50s = 12-185 and 41-280 mg/kg, respectively). Formulations containing dicloxacillin have been used prophylactically during catheterization and in dog bite patients.Formal Name: (2S,5R,6R)-6-[[[3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, monosodium salt, monohydrate. CAS Number: 13412-64-1. Molecular Formula: C19H16Cl2N3O5S . Na [H2O]. Formula Weight: 510.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 33 mg/ml, DMSO: 33 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: CC1(C)[C@H](C([O-])=O)N2C([C@@H](NC(C3=C(C)ON=C3C4=C(Cl)C=CC=C4Cl)=O)[C@@]2([H])S1)=O.[Na+].O. InChi Code: InChI=1S/C19H17Cl2N3O5S.Na.H2O/c1-7-10(12(23-29-7)11-8(20)5-4-6-9(11)21)15(25)22-13-16(26)24-14(18(27)28)19(2,3)30-17(13)24,,/h4-6,13-14,17H,1-3H3,(H,22,25)(H,27,28),,1H2/q,+1,/p-1/t13-,14+,17-,,/m1../s1. InChi Key: SIGZQNJITOWQEF-VICXVTCVSA-M.