Clindamycin hydrochloride

Clindamycin hydrochloride is a semi-synthetic, lincosamide antibiotic that is prepared from lincomycin. It inhibits bacterial protein synthesis by hydrogen bond interactions with the 23S rRNA component of the 50S ribosomal subunit thus inducing dissociation of the peptidyl-t-RNA complex. It has antibacterial activity against Gram-positive cocci and antiprotozoal activity against Taxoplasma. Clindamycin is used to study bacterial infections, such as group B streptococcal disease, bacterial resistance and plasma protein binding and used to study bacterial protein synthesis.