Cefdinir

Cefdinir is a cephalosporin antibiotic. It is active against numerous Gram-positive and Gram-negative bacteria, including beta-lactamase-producing E. coli, K. oxytoca, K. pneumoniae, and P. aeruginosa clinical isolates (MICs = 0.25-16 µg/ml). Cefdinir is protective against sepsis induced by strains of S. aureus or H. influenzae in mice with 50% protective dose (PD50) values of 2.7-35 and 3.1-5.8 mg/kg, respectively. Formulations containing cefdinir have been used in the treatment of Gram-positive and Gram-negative infections.Formal Name: (6R,7R)-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(hydroxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. CAS Number: 91832-40-5. Synonyms: BMY 28488, CI-983, FK-482. Molecular Formula: C14H13N5O5S2. Formula Weight: 395.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 0.3 mg/mL, DMSO: 2.5 mg/mL, PBS (pH 7.2): 1.25 mg/mL. lambdamax: 224, 288 nm. SMILES: C=CC1=C(C(O)=O)N2[C@]([C@H](NC(/C(C3=CSC(N)=N3)=N\O)=O)C2=O)([H])SC1. InChi Code: InChI=1S/C14H13N5O5S2/c1-2-5-3-25-12-8(11(21)19(12)9(5)13(22)23)17-10(20)7(18-24)6-4-26-14(15)16-6/h2,4,8,12,24H,1,3H2,(H2,15,16)(H,17,20)(H,22,23)/b18-7-/t8-,12-/m1/s1. InChi Key: RTXOFQZKPXMALH-GHXIOONMSA-N.