Antibiotics

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used as therapeutics in case of bacterial infections. In life science research, antibiotics are often used for selecting positive clones after transformation with recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively, antibiotics are used as inhibitors to specifically shut down certain targets, including enzymes or receptors of bacteria and cells. Here, you will find an extensive portfolio of antibiotics, from ampicillin to zelkovamycin, that you can use as inhibitors or for the selection of resistant bacteria.

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used... read more »
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Antibiotics

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used as therapeutics in case of bacterial infections. In life science research, antibiotics are often used for selecting positive clones after transformation with recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively, antibiotics are used as inhibitors to specifically shut down certain targets, including enzymes or receptors of bacteria and cells. Here, you will find an extensive portfolio of antibiotics, from ampicillin to zelkovamycin, that you can use as inhibitors or for the selection of resistant bacteria.

63 from 67 pages
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Penicillin G, Sodium Salt USP (Benzylpenicillin sodium, Sodium benzylpenicillinate)
Penicillin G, Sodium Salt USP (Benzylpenicillin sodium,...

Item number: P3200.500

Penicillin G is a broad based antibiotic used in mammalian cell culture. Penicillin G blocks the formation of bacterial cell walls, rendering bacteria unable to multiply and spread. The spectrum of activity of Penicillin G includes many aerobic and anaerobic gram-positive organisms. Aerobes susceptible to Penicillin...
CAS 69-57-8
MW: 356.37 D
From 310.00€ *
Review
Streptomycin Sulfate USP
Streptomycin Sulfate USP

Item number: S7975.100

Streptomycin Sulfate is a broad spectrum antibiotic used in mammalian cell culture. It belongs to a group of drugs called aminoglycosides. Streptomycin inhibits prokaryote protein synthesis by binding to S12 protein of 30S ribosome. It prevents the transition from initiation complex to chain-elongating ribosome and...
CAS 3810-74-0
MW: 1457.38
From 87.00€ *
Review
3-Anhydroophiobolin A (14,17-Epoxy-5-oxo-3,7,18-ophiobolatrien-21-al)
3-Anhydroophiobolin A...

Item number: A2295-22.1

3-Anhydroophiobolin A is the dehydrated analogue of ophiobolin A and is a major member of the ophiobolin complex of phytotoxic metabolites produced by many species of the genus Bipolaris. Like all ophiobolins, 3- anhydroophiobolin A possesses a broad biological profile with antibacterial, antifungal, antitumor,...
CAS 6026-65-9
MW: 382,5 D
715.00€ *
Review
Anisomycin (Flagecidin, Antibiotic SA 3097C1, Antibiotic PA 106, Anhydroscopin A, NSC)
Anisomycin (Flagecidin, Antibiotic SA 3097C1, Antibiotic...

Item number: A2296-90.100

Anisomycin is a phenylmethylenepyrrolidine first isolated from Streptomyces griseolus in 1954 as an antiprotozoan with antifungal activity. Anisomycin acts as an inhibitor of protein synthesis by binding to the 60S ribosomal subunit. Interestingly, anisomycin has found use for the induction of amnesia in animal...
CAS 22862-76-6
MW: 265,3 D
From 134.00€ *
Review
Antibiotic TPU-0037-A (30-Demethyl-lydicamycin)
Antibiotic TPU-0037-A (30-Demethyl-lydicamycin)

Item number: A2297-38M.500

TPU-0037A, a close structural analogue of lydicamycin, has been shown to be highly active against MRSA. TPU-0037A is also closely related to Antibiotic BN 4515N isolated from a strain of Microtetraspora as a neuritogenic agent. Solubility: Soluble in ethanol, methanol, DMF or DMSO. Storage and Stability: May be...
Keywords: Antibiotic
Application: Neuritogenic agent
CAS 485815-59-6
653.00€ *
Review
Antibiotic TPU-0037-C (8-Dehydroxy-30-demethyl-lydicamycin)
Antibiotic TPU-0037-C (8-Dehydroxy-30-demethyl-lydicamycin)

Item number: A2297-38N.500

TPU-0037C, a close structural analogue of lydicamycin, has been shown to be highly active against MRSA. TPU-0037C is also closely related to Antibiotic BN 4515N which was isolated from a strain of Microtetraspora as a neuritogenic agent. Purity: >95% by HPLC , Solubility: Soluble in ethanol, methanol, DMF or DMSO.,...
Keywords: Antibiotic
Application: Neuritogenic agent
CAS 485815-61-0
653.00€ *
Review
Antibiotic UCN-01 (7-Hydroxystaurosporine,  UCN-01)
Antibiotic UCN-01 (7-Hydroxystaurosporine, UCN-01)

Item number: A2297-39.1

Isolated from Streptomyces sp., Antibiotic UCN-01 inhibits protein kinase C (PKC) and cyclin-dependent kinase 2 (CDK2) resulting in accumulation of cells in the G1 phase and induction of apoptosis. UCN-01 also enhances the cytotoxicity of other anti-cancer drugs, such as DNA-damaging agents and anti-metabolite...
Keywords: Antibiotic
Application: Apoptosis inducer
CAS 112953-11-4
784.00€ *
Review
Aspercolorin
Aspercolorin

Item number: A3883-30.1

Aspercolorin is an atypical cyclic tetrapeptide in which one of the amino acids is an 5-methoxyanthranilic acid. Recently, aspercolorin has found application as a secondary metabolite standard for polyphasic taxonomy for the identication of Aspergillus versicolor. No reports of any investigation of the pharmacology...
CAS 29123-52-2
MW: 464,5 D
478.00€ *
Review
Aureothricin (Propionylpyrrothione, Farcinin)
Aureothricin (Propionylpyrrothione, Farcinin)

Item number: A4174-50.500

Aureothricin is an antibiotic first described by Umezawa and co-workers in Japan in 1949. Resurgent interest in this class of microbial metabolites was stimulated by the discovery of their selective antitumor activity. Aureothricin is a more hydrophobic analogue of thiolutin but has received only limited attention....
CAS 574-95-8
MW: 242.32 D
478.00€ *
Review
Avermectin B1a (5-O-Demethylavermectin A1a, Antibiotic C 076B1a. )
Avermectin B1a (5-O-Demethylavermectin A1a, Antibiotic C...

Item number: A4447.1

Avermectin B1a is the major component (>80%) of the commerically available anthelmintic Abamectin (R) used to control parasitic nematodes in livestock. Avermectin B1a contains a secbutyl residue in the 24-position. In vitro and in vivo studies have shown this analogue is the more potent analogue in the commerical...
CAS 65195-55-3
565.00€ *
Review
Berninamycin A (Berninamycin, Antibiotic U27810)
Berninamycin A (Berninamycin, Antibiotic U27810)

Item number: B1078-75.1

Berninamycin A is an antibiotic discovered in 1976 from a strain of Streptomyces. Berninamycin A is a macrocyclic "peptide" comprising atypical amino acids linked to thiazole and oxazoles. Chemically very complex, berninamycin A is an inducer of tipA, a gene that controls the bacterial transcription regulators,...
CAS 58798-97-3
MW: 1146.12 D
715.00€ *
Review
Berninamycin D
Berninamycin D

Item number: B1078-75D.500

Berninamycin D is an antibiotic discovered in 1994 isolated from a strain of Streptomyces as a minor analogue of berninamycin A. Berninamycin D is a macrocyclic "peptide" comprising atypical amino acids linked to thiazole and oxazoles but does not contain the didehydroalaninyl side chain present in other members of...
CAS 161263-50-9
MW: 1008.00 D
587.00€ *
Review
63 from 67 pages