Antibiotics

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used as therapeutics in case of bacterial infections. In life science research, antibiotics are often used for selecting positive clones after transformation with recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively, antibiotics are used as inhibitors to specifically shut down certain targets, including enzymes or receptors of bacteria and cells. Here, you will find an extensive portfolio of antibiotics, from ampicillin to zelkovamycin, that you can use as inhibitors or for the selection of resistant bacteria.

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used... read more »
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Antibiotics

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used as therapeutics in case of bacterial infections. In life science research, antibiotics are often used for selecting positive clones after transformation with recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively, antibiotics are used as inhibitors to specifically shut down certain targets, including enzymes or receptors of bacteria and cells. Here, you will find an extensive portfolio of antibiotics, from ampicillin to zelkovamycin, that you can use as inhibitors or for the selection of resistant bacteria.

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Althiomycin
Althiomycin

Item number: Cay32887-1

Althiomycin is a polyketide synthase-derived thiazole antibiotic originally isolated from S. althioticus. It is active against Gram-positive bacteria, including S. aureus, S. epidermidis, and S. pyogenes (MICs = 25, 25, and 3.1 µg/ml, respectively). Althiomycin inhibits protein synthesis in E. coli when used at...
Keywords: NSC 102809,...
Application: Thiazole antibiotic
CAS 12656-40-5
MW: 439.5 D
866.00€ *
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Neospiramycin I
Neospiramycin I

Item number: Cay34060-1

Neospiramycin I is a macrolide antibiotic and derivative of spiramycin I. It is active against the macrolide-sensitive KB210, but not the macrolide-resistant KB224, strain of S. aureus (MICs = 3.12 and >100 µg/ml, respectively), as well as B. cereus, B. subtilis, M. luteus, E. coli, and K. pneumoniae (MICs = 1.56,...
Keywords: 4A-O-de(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-9-O-[(2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2...
Application: Macrolide antibiotic
CAS 70253-62-2
MW: 698.9 D
From 97.00€ *
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Sancycline
Sancycline

Item number: CDX-S0344-G001

Sancycline is a semisynthetic tetracycline antibiotic that is more active than tetracycline against 339 strains of anaerobic bacteria (average MIC90s = 1 and 32 µg/ml, respectively). Sancycline is active against tetracycline-resistant E. coli, S. aureus, and E. faecalis strains with MICs ranging from 0.06 to 1...
Keywords: 6-Demethyl-6-deoxytetracycline, Bonomycin, Norcycline, GS 2147
Application: Antibacterial, Semisynthetic tetracycline antibiotic
CAS 808-26-4
MW: 414.4 D
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Cefquinome (sulfate)
Cefquinome (sulfate)

Item number: Cay34266-100

Cefquinome is a broad-spectrum cephalosporin antibiotic. It is active against clinical isolates of various Gram-positive and Gram-negative bacteria, including Salmonella, E. coli, and methicillin-resistant S. aureus (MRSA, MICs = 0.06-0.5, 0.015-0.5, and 1-16 µg/ml, respectively). Intramammary administration of...
Keywords: HR 111V sulfate,...
Application: Broad-spectrum cephalosporin antibiotic, antibacterial (veterinary), cell wall biosynthesis inhibitor
CAS 118443-89-3
MW: 626.7 D
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Cefoselis (sulfate)
Cefoselis (sulfate)

Item number: Cay34414-10

Cefoselis is a cephalosporin antibiotic. It is active against clinical isolates of extended-spectrum beta-lactamase-producing E. coli, K. pneumoniae, and P. mirabilis, as well as C. freundii, E. aerogenes, E. cloacae, S. marcescens, and P. vulgaris with susceptibility rates ranging from 56.7 to greater than 94%....
Keywords: FK-037,...
Application: Cephalosporin antibiotic, antibacterial, cell wall biosynthesis inhibitor
CAS 122841-12-7
MW: 620.6 D
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Cefalonium
Cefalonium

Item number: Cay34468-1

Cefalonium is a cephalosporin antibiotic. It is active against pooled isolates of S. aureus from the milk of lactating dairy cows with subclinical mastitis (MIC90 = 2 µg/ml). Formulations containing cefalonium have previously been used in dry cow therapy in the treatment and prevention of mastitis.Formal Name:...
Keywords: Cephalonium,...
Application: Cephalosporin antibiotic, antibacterial (veterinary), cell wall biosynthesis inhibitor
CAS 5575-21-3
MW: 458.5 D
From 153.00€ *
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Maduramicin (ammonium salt)
Maduramicin (ammonium salt)

Item number: Cay34270-100

Maduramicin is a polyether ionophore antibiotic that has been found in Nocardia. It selectively binds to potassium, rubidium, sodium, lithium, and cesium ions over divalent cations. Maduramicin is active against Gram-positive bacteria (MICs = 0.9-125 µg/ml) but not Gram-negative bacteria (MICs = >1,000 µg/ml) or...
Keywords: Antibiotic X-14868A, CL 259,971, Maduramycin, Prinicin, maduramicin alpha, monoammonium salt
Application: Polyether ionophore antibiotic, coccidiostat
CAS 84878-61-5
MW: 934.2 D
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Faropenem (sodium salt hydrate)
Faropenem (sodium salt hydrate)

Item number: Cay34507-10

Faropenem is a broad-spectrum penem antibiotic. It is active against a panel of 12 Gram-positive (MIC50s = 0.008-1 mg/L) and 15 Gram-negative (MIC50s = 0.06-16 mg/L) bacteria. Faropenem (20 mg/kg) reduces the number of lung colony forming units (CFUs) in a mouse model of H. influenzae-induced respiratory tract...
Keywords: (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furanyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic...
Application: Penem antibiotic, antibacterial, cell wall biosynthesis inhibitor
CAS 158365-51-6
MW: 352.3 D
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Kanamycin B
Kanamycin B

Item number: Cay34561-1

Kanamycin B is an aminoglycoside antibiotic. It is active against S. aureus, E. coli, P. aeruginosa, and P. rettgeri (MICs = 0.78-25 µg/ml). Kanamycin B binds to the ribosomal decoding A site to interfere with bacterial protein synthesis.Formal Name:...
Keywords: Kanamycin B, Kanendomycin, Nebramycin V,...
Application: Aminoglycoside antibiotic, antibacterial, protein biosynthesis inhibitor
CAS 4696-76-8
MW: 483.5 D
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25-Desacetyl Rifampicin
25-Desacetyl Rifampicin

Item number: Cay34817-1

25-Desacetyl rifampicin is a major active metabolite of the rifamycin antibiotic rifampicin (Cay-14423). 25-Desacetyl rifampicin is active against M. smegmatis (MIC99 = 2.66 µM).Formal Name: 25-O-deacetyl-3-[(E)-[(4-methyl-1-piperazinyl)imino]methyl]-rifamycin. CAS Number: 16783-99-6. Synonyms: Desacetylrifampicin....
Keywords: Desacetylrifampicin, 25-O-deacetyl-3-[(E)-[(4-methyl-1-piperazinyl)imino]methyl]-rifamycin
Application: Rifampicin major active metabolite
CAS 16783-99-6
MW: 780.9 D
365.00€ *
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6-Aminopenicillanic Acid
6-Aminopenicillanic Acid

Item number: Cay34494-1

6-Aminopenicillanic acid is an intermediate in the semisynthetic synthesis of penicillin antibiotics.Formal Name: (2S,5R,6R)-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid. CAS Number: 551-16-6. Synonyms: (+)-6-Aminopenicillanic Acid, 6beta-Aminopenicillanic Acid, 6-APA, NSC 50071....
Keywords: (+)-6-Aminopenicillanic Acid, 6-APA, 6beta-Aminopenicillanic Acid, NSC 50071,...
Application: Penicillin antibiotics semisynthetic synthesis intermediate
CAS 551-16-6
MW: 216.3 D
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Clindamycin (hydrochloride hydrate)
Clindamycin (hydrochloride hydrate)

Item number: Cay35581-1

Clindamycin is a lincosamide antibiotic. It is active against Gram-positive bacteria, including various strains of S. pneumoniae, S. viridans, S. aureus, and S. epidermidis (MICs = 0.002-0.1, 0.005-0.2, 0.04-1.6, and 0.1-0.2 µg/ml, respectively). Clindamycin is also active against chloroquine-resistant and...
Keywords: (2S-trans)-methyl...
Application: Lincosamide antibiotic, antibacterial, protein biosynthesis inhibitor
CAS 58207-19-5
MW: 479.5 D
From 45.00€ *
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54 from 67 pages