Antibiotics

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used as therapeutics in case of bacterial infections. In life science research, antibiotics are often used for selecting positive clones after transformation with recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively, antibiotics are used as inhibitors to specifically shut down certain targets, including enzymes or receptors of bacteria and cells. Here, you will find an extensive portfolio of antibiotics, from ampicillin to zelkovamycin, that you can use as inhibitors or for the selection of resistant bacteria.

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used... read more »
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Antibiotics

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used as therapeutics in case of bacterial infections. In life science research, antibiotics are often used for selecting positive clones after transformation with recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively, antibiotics are used as inhibitors to specifically shut down certain targets, including enzymes or receptors of bacteria and cells. Here, you will find an extensive portfolio of antibiotics, from ampicillin to zelkovamycin, that you can use as inhibitors or for the selection of resistant bacteria.

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TunR2
TunR2

Item number: Cay31538-1

TunR2 is an antibiotic and derivative of tunicamycin (Cay-11445). It is active against B. subtilis (MIC = 0.3 µg/ml) and increases the efficacy of the beta-lactam antibiotics oxacillin (Cay-23954), methicillin (Cay-21007), and penicillin G (Cay-21615) against B. subtilis when used at a concentration of 0.4 µg/ml....
Keywords: N-((2S,3R,4R,5R,6R)-2-(((2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-6-((R)-2...
Application: Antibiotic, tunicamycin derivative
From 105.00€ *
Review
Sulfaclozine (sodium salt)
Sulfaclozine (sodium salt)

Item number: Cay31223-1

Sulfaclozine is a sulfonamide antibiotic with antiprotozoal activity. Dietary administration of sulfaclozine reduces cecal lesion score and oocyst production in a chick model of E. tenella infection in a dose-dependent manner. It increases average survival time in a mouse model of T. gondii infection when...
Keywords: Sulfachloropyrazine, Sulphachloropyrazine, 4-amino-N-(6-chloro-2-pyrazinyl)-benzenesulfonamide, monosodium salt
Application: Sulfonamide antibiotic, antiprotozoal agent, coccidiostat
CAS 23307-72-4
MW: 306.7 D
From 105.00€ *
Review
TunR1
TunR1

Item number: Cay31537-1

TunR1 is an antibiotic and derivative of tunicamycin (Cay-11445). It is active against B. subtilis (MIC = 0.3 µg/ml) and increases the efficacy of the beta-lactam antibiotics oxacillin (Cay-23954), methicillin (Cay-21007), and penicillin G (Cay-21615) against B. subtilis when used at a concentration of 0.4 µg/ml....
Application: Antibiotic, tunicamycin derivative
MW: 847 D
From 105.00€ *
Review
Omadacycline
Omadacycline

Item number: Cay24932-1

Omadacycline is an aminomethylcycline antibiotic. It is active against tetracycline-susceptible and -resistant strains of S. aureus, E. faecalis, E. faecium, S. pneumoniae, and E. coli, as well as beta-hemolytic streptococci (MICs = =0.06-2 µg/ml). Omadacycline increases survival in mouse models of systemic...
Keywords: Amadacycline, BAY 73-7388, MK-2764,...
Application: Aminomethylcycline antibiotic, tetracycline antibiotic, protein biosynthesis inhibitor
CAS 389139-89-3
MW: 556.7 D
From 76.00€ *
Review
HSGN-218
HSGN-218

Item number: Cay32711-1

HSGN-218 is a gut-restrictive antibiotic. It is active against C. difficile (MIC = 0.007 µg/ml) and clinical isolates of C. difficile (MICs = 0.003-0.03 µg/ml) and is not cytotoxic to Caco-2 cells when used at concentrations ranging from 4 to 64 µg/ml. HSGN-218 (50 mg/kg) increases survival and protects mice from C....
Keywords: N-(5-(3,5-dichlorophenyl)-1,3,4-oxadiazol-2-yl)-4-((trifluoromethyl)thio)benzamide
Application: Gut-restrictive antibiotic
CAS 2519410-44-5
MW: 434.2 D
From 40.00€ *
Review
Oxolinic Acid
Oxolinic Acid

Item number: LKT-O9458.1

A quinolone antibiotic agent that inhibits the enzyme DNA gyrase. Also may act as a dopamine reuptake inhibitor.
Application: DNA gyrase inhibitor
CAS 14698-29-4
MW: 261.23 D
82.00€ *
Review
Cefotiam (hydrochloride hydrate)
Cefotiam (hydrochloride hydrate)

Item number: Cay32871-1

Cefotiam is a broad-spectrum cephalosporin antibiotic. It inhibits the growth of the Gram-positive bacterium S. aureus (MIC50 = 0.26 µg/ml) and the Gram-negative bacteria P. aeruginosa, E. coli, and H. influenzae (MIC50s = 1, 0.06, and 0.01 µg/ml, respectively). Cefotiam increases survival in mouse models of...
Keywords: Cephotiam, CGP 14221, CGP 14221/E, SCE 963,...
Application: Broad-spectrum cephalosporin antibiotic, antibacterial, cell wall biosynthesis inhibitor
MW: 598.5 D
From 187.00€ *
Review
Cephalosporin C (zinc)
Cephalosporin C (zinc)

Item number: Cay33262-10

Cephalosporin C is a fungal metabolite and cephalosporin antibiotic that has been found in Cephalosporium. It is active against a variety of bacteria, including S. pyogenes, C. diphtheriae, E. coli, and H. influenzae (MICs = 31, 15.6, 125, and 31 µg/ml, respectively), as well as clinical isolates of N. gonorrhoeae...
Keywords: 3-[(acetyloxy)methyl]-7-[[(5R)-5-amino-5-carboxy-1-oxopentyl]amino]-8-oxo-(6R,7R)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-ca...
Application: Cephalosporin antibiotic
CAS 59143-60-1
MW: 478.8 D
From 133.00€ *
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Aranciamycin A
Aranciamycin A

Item number: Cay31659-2.5

Aranciamycin A is an anthracyclic antibiotic that has been found in Streptomyces. It is active against M. bovis and B. subtilis (MICs = 30 and 7.5 µM, respectively) but not S. aureus, E. coli, P. aeruginosa, or C. albicans (MICs = >30 µM for all).Formal Name:...
Keywords: (8R,10S)-10-[(6-deoxy-2-O-methyl-alpha-L-mannopyranosyl)oxy]-7,8,9,10-tetrahydro-1,8,11-trihydroxy-8-methyl-5,12-naphthace...
Application: Antibiotic
CAS 960622-70-2
MW: 500.5 D
From 409.00€ *
Review
Metronidazole Benzoate
Metronidazole Benzoate

Item number: Cay33316-1

Metronidazole benzoate is an antibiotic and antiprotozoal agent and ester form of metronidazole (Cay-9002409). It is active against P. asaccharolyticus, C. perfringens, C. septicum, B. fragilis, and B. thetaiotaomicron (MICs = 3.6, 7.3, 1.8, 7.3, and 7.3 µM, respectively). Metronidazole reduces parasitemia in rats...
Keywords: Benzoylmetronidazole, 2-methyl-5-nitro-1H-imidazole-1-ethanol 1-benzoate
Application: Antibiotic, antiprotozoal agent, DNA synthesis inhibitor
CAS 13182-89-3
MW: 275.3 D
From 69.00€ *
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Pseudomonic Acid (lithium salt)
Pseudomonic Acid (lithium salt)

Item number: Cay33271-10

Pseudomonic acid is an antibiotic and bacterial metabolite that has been found in P. fluorescens. It is bacteriostatic against S. aureus (MIC = 0.05 µg/ml) and active against skin wound clinical isolates of methicillin-resistant S. aureus (MRSA, MICs = 1-4 µg/ml). Pseudomonic acid inhibits MRSA and P. aeruginosa...
Keywords: 5,9-anhydro-2,3,4,8-tetradeoxy-8-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]-2-oxiranyl]methyl]-3-methyl-L-talo-non-2-e...
Application: Antibiotic
CAS 73346-79-9
MW: 506.6 D
From 164.00€ *
Review
Althiomycin
Althiomycin

Item number: Cay32887-1

Althiomycin is a polyketide synthase-derived thiazole antibiotic originally isolated from S. althioticus. It is active against Gram-positive bacteria, including S. aureus, S. epidermidis, and S. pyogenes (MICs = 25, 25, and 3.1 µg/ml, respectively). Althiomycin inhibits protein synthesis in E. coli when used at...
Keywords: NSC 102809,...
Application: Thiazole antibiotic
CAS 12656-40-5
MW: 439.5 D
866.00€ *
Review
53 from 67 pages