Antibiotics

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used as therapeutics in case of bacterial infections. In life science research, antibiotics are often used for selecting positive clones after transformation with recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively, antibiotics are used as inhibitors to specifically shut down certain targets, including enzymes or receptors of bacteria and cells. Here, you will find an extensive portfolio of antibiotics, from ampicillin to zelkovamycin, that you can use as inhibitors or for the selection of resistant bacteria.

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used... read more »
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Antibiotics

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used as therapeutics in case of bacterial infections. In life science research, antibiotics are often used for selecting positive clones after transformation with recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively, antibiotics are used as inhibitors to specifically shut down certain targets, including enzymes or receptors of bacteria and cells. Here, you will find an extensive portfolio of antibiotics, from ampicillin to zelkovamycin, that you can use as inhibitors or for the selection of resistant bacteria.

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Gilvocarcin M
Gilvocarcin M

Item number: Cay25762-2.5

Gilvocarcin M is an antibiotic originally isolated from S. gilvotanareus. It is active against S. aureus when used at a concentration of 32 µg/ml. Gilvocarcin M inhibits growth of KB cells (IC50 = 0.52 µg/ml) but has no effect on survival in a P388 mouse model of leukemia when used at doses ranging from 25 to 400...
Keywords: Antibiotic 1072A,...
Application: Antibiotic
CAS 77879-89-1
MW: 482.5 D
From 498.00€ *
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Drimentine C
Drimentine C

Item number: Cay25763-1

Drimentine C is a terpenylated diketopiperazine antibiotic originally isolated from Actinomycete bacteria. It inhibits proliferation of NS-1 murine beta lymphocyte myeloma cells by 63 and 98% in vitro when used at concentrations of 12.5 and 100 µg/ml, respectively.Formal Name:...
Keywords: (5aS,6aS,11aS,13aS)-6a-[[(1S,4aS,8aS)-decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl]methyl]-2,3,6,6a,11,11a-hexahy...
Application: Antibiotic
CAS 204398-92-5
MW: 487.7 D
From 427.00€ *
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Totarol
Totarol

Item number: Cay26412-100

Totarol is a diterpene originally isolated from P. totara that has diverse biological activities, including antibacterial, antioxidant, and neuroprotective properties. It is active against Gram-positive bacteria, including P. acnes, S. mutans, B. subtilis, and B. ammoniagenes (MICs = 0.39, 0.78, 1.56, and 0.78...
Keywords: (+)-Totarol, trans-Totarol, NSC 299936,...
Application: Bioactive, antibacterial, antioxidant, neuroprotective diterpene
CAS 511-15-9
MW: 286.5 D
From 62.00€ *
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Chloramphenicol Palmitate
Chloramphenicol Palmitate

Item number: Cay26663-25

Chloramphenicol palmitate is an orally bioavailable ester prodrug form of the antibiotic chloramphenicol. It is hydrolyzed in the small intestine to release chloramphenicol. Formulations containing chloramphenicol palmitate were previously used in the treatment of severe bacterial infections.Formal Name:...
Keywords: hexadecanoic acid, (2R,3R)-2-[(2,2-dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl ester
Application: Antibiotic ester prodrug
CAS 530-43-8
MW: 561.5 D
From 166.00€ *
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Dihydropleuromutilin
Dihydropleuromutilin

Item number: Cay26497-25

Dihydropleuromutilin is a semisynthetic antibiotic and derivative of pleuromutilin (Cay-19452). It is active against S. aureus, M. hominis, M. gallisepticum, and M. hyorhinis bacteria (MICs = 0.5, 0.3, 0.3, and 2 µg/ml, respectively).Formal Name: 2-hydroxy-acetic acid,...
Keywords: (+)-19,20-Dihydropleuromutilin, 2-hydroxy-acetic acid,...
Application: Antibiotic
CAS 42302-24-9
MW: 380.5 D
From 180.00€ *
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Zelkovamycin
Zelkovamycin

Item number: Cay27753-1

Zelkovamycin is a cyclic peptide antibiotic originally isolated from Streptomyces. It inhibits growth of X. oryzae, P. oryzae, S. aureus, and A. laidlawii in a concentration-dependent manner when used at concentrations ranging from 0.01 to 300 µg/ml.CAS Number: 221197-33-7. Molecular Formula: C36H45N9O9S. Formula...
Keywords: zelkovamycin
Application: Cyclic peptide antibiotic
CAS 221197-33-7
MW: 779.9 D
From 169.00€ *
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Epianhydrotetracycline (hydrochloride)
Epianhydrotetracycline (hydrochloride)

Item number: Cay27954-1

Epianhydrotetracycline (EATC) is a degradation product of the antibiotic tetracycline (Cay-14328). EATC is active against Pseudomonas, Agrobacterium, Moraxella, Bacillus, and E. coli (MIC50s = 0.75-16 mg/L).Formal Name:...
Keywords: EATC,...
Application: Tetracycline degradation product, antibiotic
CAS 4465-65-0
MW: 462.9 D
From 51.00€ *
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Sancycline (hydrochloride)
Sancycline (hydrochloride)

Item number: Cay28118-100

Sancycline is a semisynthetic tetracycline antibiotic that is more active than tetracycline (Cay-14328) against 339 strains of anaerobic bacteria (average MIC90s = 1 and 32 µg/ml, respectively). Sancycline is active against tetracycline-resistant E. coli, S. aureus, and E. faecalis strains with MICs ranging from...
Keywords: 6-Demethyl-6-deoxytetracycline, NSC 51812,...
Application: Antibacterial tetracycline antibiotic
CAS 6625-20-3
MW: 450.9 D
From 55.00€ *
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Tobramycin, Free Base
Tobramycin, Free Base

Item number: LKT-T5604.100

Aminoglycoside, protein translation inhibitor.
Keywords: Nebramycin factor 6, NF 6, Tobracin, Tobralex, Tobramaxin, Tobrex, O-3-Amino-3-deoxy-alpha-d-glucopyranosyl-(1->6)-O-...
Application: Protein synthesis inhibitor
CAS 32986-56-4
MW: 467,51 D
From 96.00€ *
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Streptogramin B
Streptogramin B

Item number: Cay28086-1

Streptogramin B is a macrolide antibiotic. It inhibits the growth of Clostridium, Peptostreptococcus, and Propionibacterium bacterial species (MIC90s = 2, 0.5, and 8 µg/ml, respectively). Streptogramin B inhibits protein synthesis by interacting with the 50S ribosome. Resistance to streptogramin B is conferred by...
Keywords: Mikamycin IA, NSC 92554, Ostreogrycin B, Pristinamycin IA, Vernamycin Balpha, Virginiamycin B,...
Application: Macrolide antibiotic
CAS 3131-03-1
MW: 867 D
From 107.00€ *
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PNU 100480
PNU 100480

Item number: Cay28395-10

PNU 100480 is an oxazolidinone antibiotic that is active against multidrug resistant tuberculosis. It inhibits the growth of M. tuberculosis replicating and nonreplicating strains (MIC = ~400 ng/ml for both) and of clinical isolates that are susceptible or resistant to a combination of isoniazid (Cay-20378),...
Keywords: Sutezolid, U 100480, N-[[(5S)-3-[3-fluoro-4-(4-thiomorpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-acetamide
Application: Oxazolidinone antibiotic
CAS 168828-58-8
MW: 353.4 D
From 133.00€ *
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Sulfamoxole
Sulfamoxole

Item number: Cay19537-100

Sulfamoxole is a sulfonamide antibiotic. It is inactive or weakly active against bacteria when used alone but acts synergistically with trimethoprim (Cay-16473) against a variety of bacteria in vitro, including strains of S. pyogenes, E. coli, and P. vulgaris when used at concentrations of 1.95-7.8, 0.12-1.95, and...
Keywords: NSC 683535, 4-amino-N-(4,5-dimethyl-2-oxazolyl)-benzenesulfonamide
Application: Sulfonamide antibiotic, antibacterial, folic acid biosynthesis inhibitor
CAS 729-99-7
MW: 267.3 D
From 76.00€ *
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51 from 67 pages