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Concanamycin B
Item number: Cay15502-1
Concanamycin B is a macrolide antibiotic originally isolated from Streptomyces that selectively inhibits vacuolar type H+-ATPases, also known as V-ATPases (IC50 = 5 nM). In this way, it blocks the acidification of vacuolar organelles as well as early to late endosomal transport. Concanamycin B interferes with bone...
| Keywords: | 8-deethyl-8-methyl-Concanamycin A, MCH 210,... |
| Application: | Macrolide-type antibiotic, V-ATPase inhibitor |
| CAS | 81552-33-2 |
| MW: | 852.1 D |
From 345.00€
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Pseudoerythromycin A enol ether
Item number: Cay15508-1
Pseudoerythromycin A enol ether is a degradation product of the macrolide antibiotic erythromycin (Cay-16486). It promotes monocyte differentiation into macrophages when used at a concentration of 10 µM.Formal Name:...
| Keywords: | LY267108,... |
| Application: | Erythromycin degradation product |
| CAS | 105882-69-7 |
| MW: | 715.9 D |
From 151.00€
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Kazusamycin A
Item number: Cay20137-100
Kazusamycin A is an antibiotic from Streptomyces and a hydroxy analog of Leptomycin B (Cay-10004976) that demonstrates cytotoxic activity against various human and mouse tumor lines. Additionally, at nanomolar concentrations, it inhibits nuclear export and translocation of Rev, a regulatory gene product in the HIV...
| Keywords: | CL 1,957B, Hydroxyelactocin, Hydroxyleptomycin B, PD 114721,... |
| Application: | Antibiotic |
| CAS | 92090-94-3 |
| MW: | 556.7 D |
From 534.00€
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Oligomycin E
Item number: Cay20185-1
Oligomycin E is a minor metabolite of the oligomycin complex (Cay-11341) produced by several species of Streptomyces. It exhibits relatively weak antifungal activity compared to other oligomycins, yet is active against Gram-positive bacteria and demonstrates strong antitumor activity against HeLa cells (IC50 = 14...
| Keywords: | 26-hydroxy-28-oxo-Oligomycin A,... |
| Application: | Antibacterial (gram-positive), antitumor |
| CAS | 110231-34-0 |
| MW: | 821.1 D |
From 465.00€
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PC-766B
Item number: Cay20587-1
PC-766B is a macrolide antibiotic produced by N. brasiliensis that is active against Gram-positive bacteria and some fungi, yet inactive against Gram-negative bacteria. It also demonstrates antitumor activity against mouse P388 leukemia and B16 melanoma cells in vitro (IC50s = 0.1 and 0.4 ng/ml, respectively) and in...
| Keywords: | Antibiotic PC-766B,... |
| Application: | Macrolide antibiotic |
| CAS | 108375-77-5 |
| MW: | 777 D |
From 351.00€
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Thiamphenicol
Item number: Cay21357-10
Thiamphenicol is an antibiotic derived from chloramphenicol that displays a similar spectrum of activity with enhanced potency. It displays good in vitro activity against a range of multidrug resistant pathogens, including penicillin-resistant strains and methicillin-resistant S. aureus.Formal Name:...
| Keywords: | (+)-Thiamphenicol, NSC 522822, Thiophenicol, WIN 5,603-2,... |
| Application: | Antibiotic |
| CAS | 15318-45-3 |
| MW: | 356.2 D |
From 89.00€
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Tylosin
Item number: Cay22599-10
Tylosin is a macrolide antibiotic produced by S. fradiae that has bacteriostatic activity against Gram-positive bacteria. It is a mixture of tylosin A, B, C, and D, with tylosin A contributing 80% of its bacteriostatic activity. Tylosin has MIC values of 9.6, 16.4, 0.1, 1, and 0.5 µg/ml for F. necrophorum, A....
| Keywords: | tylosin |
| Application: | Macrolide bacteriostatic antibiotic |
| CAS | 1401-69-0 |
| MW: | 916.1 D |
From 40.00€
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TAK-599
Item number: Cay23696-1
TAK-599 is a prodrug of T-91825, a cephalosporin antibiotic. In vitro, TAK-599 inhibits growth of S. pneumoniae, S. aureus, methicillin-resistant S. aureus (MRSA), E. coli, and K. pneumoniae (MICs = 0.008-2 mg/L). It is rapidly converted to T-91825 in rats and monkeys. TAK-599 has bacteriostatic effects in mice...
| Keywords: | 4-[2-[[(6R,7R)-2-carboxy-7-[[(2Z)-2-(ethoxyimino)-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-8-oxo-5-thia-1... |
| Application: | Antibiotic prodrug |
| CAS | 400827-46-5 |
| MW: | 744.7 D |
From 97.00€
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Gliorosein
Item number: Cay24921-1
Gliorosein is a fungal metabolite produced by Gliocladium. It is an isomer of rubrogliocladin hydroquinone. Gliorosein has antibiotic activity against B. allii, B. subtilis, and E. coli.Formal Name: (4R,5S,6S)-4-hydroxy-2,3-dimethoxy-5,6-dimethyl-2-cyclohexen-1-one. CAS Number: 2673270-41-0. Molecular Formula:...
| Keywords: | 2,3-dimethoxy-5S,6S-dimethyl-2-cyclohexene-1,4-dione |
| Application: | Fungal metabolite, antibiotic |
| CAS | 2673270-41-0 |
| MW: | 198.2 D |
From 283.00€
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Chromomycin A3
Item number: LKT-C2969.1
The major component of a streptomycete contaminant in a marine fungal culture that is an aureolic acid derivative that is a minor groove DNA-binding antibiotic.
| Application: | Metabolic studies |
| CAS | 7059-24-7 |
| MW: | 1183,25 D |
From 143.00€
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Clindamycin palmitate HCl
Item number: LKT-C4534.10
An inactive molecule which is hydrolyzed into its active form by small intestinal enzymes.
| Application: | Metabolic studies |
| CAS | 25507-04-4 |
| MW: | 663,39 D |
From 150.00€
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Enrofloxacin
Item number: LKT-E5369.10
Light yellow to light orange crystals. A plant fungicide and antibacterial agent.
| Application: | Antibacterial agent |
| CAS | 93106-60-6 |
| MW: | 359,39 D |
From 125.00€
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