Antibiotics

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used as therapeutics in case of bacterial infections. In life science research, antibiotics are often used for selecting positive clones after transformation with recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively, antibiotics are used as inhibitors to specifically shut down certain targets, including enzymes or receptors of bacteria and cells. Here, you will find an extensive portfolio of antibiotics, from ampicillin to zelkovamycin, that you can use as inhibitors or for the selection of resistant bacteria.

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used... read more »
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Antibiotics

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used as therapeutics in case of bacterial infections. In life science research, antibiotics are often used for selecting positive clones after transformation with recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively, antibiotics are used as inhibitors to specifically shut down certain targets, including enzymes or receptors of bacteria and cells. Here, you will find an extensive portfolio of antibiotics, from ampicillin to zelkovamycin, that you can use as inhibitors or for the selection of resistant bacteria.

43 from 67 pages
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Fridamycin B
Fridamycin B

Item number: BVT-0470-M001

Yellow solid. Soluble in DMSO. Sparingly soluble in methanol or acetone. C-glycosidic angucyclinone derivative, Antibiotic, Antitumor agent, Antibacterial agent, Isomer of fridamycin A (Prod. No. BVT-0469).
Keywords: 3'-Epimer of Fridamycin A
Application: Antibiotic
MW: 486,5 D
From 100.00€ *
Review
Chrysomycin A
Chrysomycin A

Item number: Cay14188-1

Chrysomycin A is an antibiotic isolated from a strain of Streptomyces. It is structurally very similar to gilvocarcin V, an inhibitor of topoisomerase II which promotes DNA cross-linking with histone 3 and GRP78 when photoactivated by near-UV light. Chrysomycin A inhibits DNA synthesis in bacteria and suppresses the...
Keywords: Albacarcin V, NSC 613946, Virenomycin V,...
Application: Topoisomerase II inhibitor
CAS 82196-88-1
MW: 508.5 D
From 212.00€ *
Review
Aureothricin
Aureothricin

Item number: Cay19942-1

Aureothricin is a dithiolopyrrolone antibiotic first isolated from Streptomyces sp. that exhibits broad-spectrum antimicrobial activity against many Gram-positive and Gram-negative bacteria, as well as strains of M. tuberculosis. It is also reported to inhibit tumor angiogenesis, blocking activity of the vitronectin...
Keywords: Farcinicin, Propionylpyrrothione, N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)-propanamide
Application: Antibacterial antibiotic
CAS 574-95-8
MW: 242.3 D
From 218.00€ *
Review
Teicoplanin A2-5
Teicoplanin A2-5

Item number: Cay20192-1

Teicoplanin A2-5 is a glycopeptide antibiotic produced by A. teichomyceticus that is broadly effective against Gram-positive bacteria in vitro. It is the most non-polar metabolite in the family of teicoplanins.Formal Name:...
Keywords: 34-O-[2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(9-...
Application: Glycopeptide antibiotic, antibacterial (gram-positive)
CAS 91032-38-1
MW: 1893.7 D
From 371.00€ *
Review
Sandramycin
Sandramycin

Item number: Cay20575-1

Sandramycin is a cyclic depsipeptide antibiotic that was first isolated from the culture broth of Nocardioides sp. It is active against Gram-positive bacteria in vitro and leukemia P388 tumors in mice. Sandramycin acts as a bifunctional DNA intercalator that strongly binds DNA and forms crosslinks between DNA...
Keywords: (-)-Sandramycin,...
Application: Antibiotic, DNA intercalator & crosslinker
CAS 100940-65-6
MW: 1221.3 D
From 574.00€ *
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21-hydroxy Oligomycin A
21-hydroxy Oligomycin A

Item number: Cay20599-1

21-hydroxy Oligomycin A is an antibiotic that was first isolated from S. cyaneogriseus ssp. noncyanogenus (LL-F28249). It is reported to be cytotoxic to human colon cancer SW620 cells (IC50 = 14.4 µM), to inhibit the ABC transporter efflux pump P-glycoprotein, and to prevent K-Ras plasma membrane localization (IC50...
Keywords: (1R,2'S,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,28S,29R)-22-ethyl-3',4',5',6'-tetrahydro-7,11,14,15,23...
Application: Antibiotic
CAS 102042-09-1
MW: 807.1 D
From 509.00€ *
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Nornidulin
Nornidulin

Item number: Cay23646-1

Nornidulin is a depsidone originally isolated from A. nidulans that has antibacterial activity against M. tuberculosis and M. ranoe as well as antifungal activity against T. tonsurans and M. audouini. It also inhibits the growth of methicillin-resistant S. aureus (MRSA, MIC = 2 µg/ml). Nornidulin has cytotoxic...
Keywords: 2,4,7-trichloro-3,8-dihydroxy-1,9-dimethyl-6-(1-methyl-1-propen-1-yl)-11H-dibenzo[b,e][1,4]dioxepin-11-one
Application: Antibacterial, antifungal, cytotoxic
CAS 33403-37-1
MW: 429.7 D
From 345.00€ *
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Saccharocarcin B
Saccharocarcin B

Item number: Cay23861-2.5

Saccharocarcin B is a macrocyclic lactone antibiotic that is active against the Gram-positive bacteria M. luteus and S. aureus as well as the Gram-negative bacteria C. trachomatis.Formal Name:...
Keywords: 10-[[4-(acetylamino)-2,4,6-trideoxy-3-C-methylhexopyranosyl]oxy]-4-[[O-2,6-dideoxyhexopyranosyl-(1->4)-O-2,6-dideoxy-3-O-(...
Application: Macrocyclic lactone antibiotic
CAS 158475-33-3
MW: 1254.5 D
From 371.00€ *
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Besifloxacin HCl
Besifloxacin HCl

Item number: LKT-B1973.100

Besifloxacin is a 4th generation fluoroquinolone antibiotic that has broad-spectrum activity against aerobic and anaerobic bateria. It is more effective than gatifloxacin and moxifloxacin in reducing MRSA in the rabbit cornea.
Keywords: 7-[(3R) -3-aminoazepam- 1-yl]- 8-chloro- 1-cyclopropyl- 6-fluoro- 4-oxo- 1,4- dihydroquinoline- 3-carboxylic acid...
Application: DNA gyrase inhibitor, Topoisomerase IV inhibitor
CAS 405165-61-9
MW: 430.31 D
From 184.00€ *
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Cefaclor, Monohydrate
Cefaclor, Monohydrate

Item number: LKT-C1627.1

Antimicrobial agent. It has a broad spectrum of activity against the most prevalent gram- positive and gram-negative respiratory tract pathogens.
Application: Antimicrobial agent
CAS 70356-03-5
MW: 385,83 D
From 136.00€ *
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Clindamycin phosphate
Clindamycin phosphate

Item number: LKT-C4533.10

The 2-dihydrogen phosphate analog of Clindamycin.
Application: Metabolic studies
CAS 24729-96-2
MW: 504,96 D
From 100.00€ *
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Marbofloxacin
Marbofloxacin

Item number: LKT-M0368.1

A quinolone, and acts by inhibiting bacterial DNA replication.
Keywords: Zeniquin,...
Application: Bacterial DNA replication inhibitor
CAS 115550-35-1
MW: 362.36 D
From 187.00€ *
Review
43 from 67 pages