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Doxycycline (hyclate)
Item number: Cay14422-1
Doxycycline is a broad-spectrum tetracycline antibiotic. It inhibits bacterial protein synthesis by binding to ribosomes. Doxycycline also selectively inhibits human matrix metalloproteinase-8 (MMP-8) and MMP-13 over MMP-1 with 50, 60, and 5% inhibition, respectively, when used at a concentration of 30 µM. It can be...
| Keywords: | (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-... |
| Application: | Antibiotic |
| CAS | 24390-14-5 |
| MW: | 1025.9 D |
From 60.00€
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Antibiotic PF 1052
Item number: BVT-0338-M001
Antibiotic, Antibacterial, antifungal and phytotoxic. Isolated from Phoma sp.
| Keywords: | (E)-5-(sec-Butyl)-3-((2-(2,3-dimethyloxiran-2-yl)-6,8-dimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl)(hydroxy)methyle... |
| Application: | Bioassays |
| CAS | 147317-15-5 |
| MW: | 429,6 D |
From 125.00€
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Chloramphenicol (Chloromycetin)
Item number: C4350.1
Chloramphenicol is a chlorine-containing antibiotic produced by Streptomyces venezuelae. It has a wide spectrum of activity against gram-positive and gram-negative cocci and bacilli (including anaerobes), Rickettsia, Mycoplasma, and Chlamydia. It inhibits prokaryotic protein synthesis by attaching to the 50S...
| CAS | 56-75-7 |
| MW: | 323.13 D |
From 87.00€
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Gamithromycin
Item number: Cay23389-25
Gamithromycin is an antibiotic that is active against macrolide-resistant R. equi and S. zooepidemicus (MIC90s = 1 and 0.125 µg/ml, respectively). It reduces the number of pneumonic lesions in a bovine M. haemolytica challenge model at a dose of 6 mg/kg. Formulations containing gamithromycin have been used to treat...
| Keywords: | ML-1709460,... |
| Application: | Antibiotic |
| CAS | 145435-72-9 |
| MW: | 777 D |
From 126.00€
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GE2270A
Item number: AG-CN2-0303-M001
Isolated from Planobispora rosea. White to off-white powder. Soluble in DMSO or other organic solvents. Thiopeptide antibiotic. Antibacterial agent by inhibiting bacterial protein synthesis. Active against numerous Gram-positive pathogens, including methicillin-resistant strains of Staphylococcus aureus and...
| Keywords: | Antibiotic GE 2270A, MDL 62879 |
| Application: | Thiopeptide antibiotic, EF-Tu inhibitor |
| CAS | 134861-34-0 |
| MW: | 1290.5 D |
From 105.00€
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Thiocillin I
Item number: Cay26681-500
Thiocillin I is an antibiotic originally isolated from Bacillus that has activity against Gram-positive, but not Gram-negative, bacteria. It inhibits the growth of B. subtilis, B. anthracis, S. aureus, S. pyogenes, and S. pneumoniae strains in vitro (MICs = 0.2-3.13 µg/ml). Thiocillin I exhibits antibiotic activity...
| Keywords: | 44-O-Demethylthiocillin II,... |
| Application: | Antibiotic |
| CAS | 59979-01-0 |
| MW: | 1160.4 D |
From 421.00€
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Mithramycin A
Item number: Cay11434-1
Mithramycin A is a DNA-binding, anti-tumor and neuroprotective antibiotic originally isolated from S. grieseus that has long been used as a chemotherapeutic agent. It mediates its protective function, in part, by regulating acetylation of histones or transcription factors and, thereby, chromatin accessibility to...
| Keywords: | A 2371, Antibiotic LA 7017, Aureolic Acid, NSC 24559, PA 144, Plicamycin,... |
| Application: | Antibiotic, SP1 inhibitor |
| CAS | 18378-89-7 |
| MW: | 1085.2 D |
From 76.00€
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Antimycin A
Item number: LKT-A5378.10
White powder. An inhibitor of mitochondrial respiratory chain complex III. Induces apoptosis in cell cultures.
| Application: | Apoptosis inducer |
| CAS | 1397-94-0 |
| MW: | 548,63 D |
From 199.00€
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Blasticidin S (hydrochloride)
Item number: Cay14499-50
Blasticidin S is a peptidyl nucleoside antibiotic. It was first isolated from S. griseochromogenes. The structure of the pentahydrate form was determined using diffractometer data and, similar to the antibiotic amicetin, the hydrophilic and hydrophobic groups lie on either side of the molecule. It has since been...
| Keywords: | 4-[[(3S)-3-amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl]amino]-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeo... |
| Application: | Antibiotic |
| CAS | 3513-03-9 |
| MW: | 458.9 D |
From 70.00€
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Actinomycin D
Item number: BVT-0089-M005
Antibiotic, Antitumor compound, Cytotoxic, Apoptosis inducer, RNA synthesis inhibitor, DNA intercalating agent, Mcl-1 expression inhibitor, p53 pathway activator. Isolated from Streptomyces parvulus.
| Keywords: | Actinomycin IV, Actinomycin C1, Dactinomycin |
| Application: | p53 pathway activator |
| CAS | 50-76-0 |
| MW: | 1255,4 D |
From 55.00€
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Minocycline (hydrochloride hydrate)
Item number: Cay14454-100
Minocycline is a broad-spectrum tetracycline antibiotic. It is active against E. faecium in vitro (MIC = 16 mg/L). Minocycline (20 mg/kg every 12 hours) reduces the number of bacteria in the lung in a mouse model of multidrug resistant A. baumannii-induced pneumonia. It reduces spinal cord lesion size and improves...
| Keywords: | NSC 141993,... |
| Application: | Antibiotic |
| MW: | 493.9 D |
From 62.00€
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Alamethicin
Item number: Cay11425-1
Alamethicin is an antibiotic peptide belonging to a class of membrane active peptides of fungal origin called peptaibols. It contains an unusual amphiphilic amino acid, 2-aminoisobutyric acid, which strongly induces helical peptide structures and forms voltage-gated ion channels in the lipid bilayers of cell...
| Keywords: | Antibiotic U-22324,... |
| Application: | Ion channel assembly studies |
| CAS | 27061-78-5 |
| MW: | 1964.3 D |
From 85.00€
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