6-Deoxy-8-O-methylrabelomycin

6-Deoxy-8-O-methylrabelomycin is an anthraquinone that has been found in Pseudonocardia with antiparasitic and antibiotic activities. It is active against the parasite P. berghei (IC50 = 18.5 µM) and the bacterium B. subtilis (MIC = 25 µg/ml) but does not induce cellular toxicity in HepG2 cells (IC50 = >100 µM). 6-Deoxy-8-O-methylrabelomycin is also active against methicillin-resistant S. aureus (MRSA, IC50 = 48 µg/ml) and reduces MRSA production of the virulence factor staphyloxanthin (IC50 = 6 µg/ml).Formal Name: 3R,4-dihydro-3-hydroxy-8-methoxy-3-methyl-benz[a]anthracene-1,7,12(2H)-trione. CAS Number: 117620-87-8. Synonyms: (-)-8-O-Methyltetrangomycin, MM 47755. Molecular Formula: C20H16O5. Formula Weight: 336.3. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Acetonitrile: Slightly soluble: 0.1-1 mg/ml, Methanol: Slightly soluble: 0.1-1 mg/ml. SMILES: O=C1C2=C(C=CC3=C2C(C4=CC=CC(OC)=C4C3=O)=O)C[C@](O)(C)C1. InChi Code: InChI=1S/C20H16O5/c1-20(24)8-10-6-7-12-17(15(10)13(21)9-20)19(23)11-4-3-5-14(25-2)16(11)18(12)22/h3-7,24H,8-9H2,1-2H3/t20-/m1/s1. InChi Key: XZLGWJORNHETKI-HXUWFJFHSA-N. Origin: Bacterium/Streptomyces sp. Gö 40/14.