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Item number: Cay10010622-25
Uncoupling protein 2 (UCP2) is a mitochondrial carrier protein that is expressed in pancreatic islets and has been shown to negatively regulate glucose-stimulated insulin secretion. High levels of UCP2 expression can disrupt pancreatic beta cell function and downregulate insulin secretion thereby contributing to the...
| Keywords: | (+)-Genipin, 1R,4aS,5,7aS-tetrahydro-1-hydroxy-7-(hydroxymethyl)-cyclopenta[c]pyran-4-carboxylic acid, methyl ester |
| Application: | UCP2 inhibitor |
| CAS | 6902-77-8 |
| MW: | 226.2 D |
From 29.00€
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Item number: Cay90410-25
Lipoxin A4 (LXA4) is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of (±)15-HETE (Cay-34700) or 15-HpETE with human leukocytes. LXA4 is equipotent to leukotriene B4 (Cay-20110) in inducing superoxide generation in human neutrophils at 0.1 µM. LXA4 is associated with several...
| Keywords: | 5(S),6(R),15(S)-TriHETE, LXA4, 5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 89663-86-5 |
| MW: | 352.5 D |
From 319.00€
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Item number: Cay16494-5
n-Dodecyl-beta-D-maltoside (DDM) is a non-ionic detergent commonly used to solubilize membrane-associated proteins. In particular, it helps retain the native conformation and activity of membrane-associated proteins, and facilitates the reforming of these proteins after denaturation. The critical micelle...
| Keywords: | DDM, Dodecyl Maltoside, dodecyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside |
| Application: | Non-ionic detergent |
| CAS | 69227-93-6 |
| MW: | 510.6 D |
From 98.00€
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Item number: ABD-151
Ex: 649 nm. Em: 665 nm. Soluble in: DMSO. A variety of cyanine 5 ( Cy5(R)) dyes has been used to label biological molecules for fluorescence imaging and other fluorescence-based biochemical analysis. They are widely used for labeling peptides, proteins and oligos etc. Cy5® dyes are one type of the most common red...
| Application: | Labeling probe, classic labeling dye, cyanine |
| MW: | 855,07 D |
From 114.00€
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Item number: Cay314010-50
Prostaglandin E2-d4 (PGE2-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of PGE2 by GC- or LC-mass spectrometry. PGE2 is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely investigated...
| Keywords: | Dinoprostone-d4, PGE2-d4, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic-3,3,4,4-d4 acid |
| Application: | Standard |
| CAS | 34210-10-1 |
| MW: | 356.5 D |
From 107.00€
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Item number: Cay90050-5
Arachidonoyl ethanolamide (AEA) is the ethanolamine amide of arachidonic acid, originally isolated from porcine brain. AEA is an endogenous cannabinoid neurotransmitter that binds to both cannabinoid 1 (CB1) and CB2 receptors. AEA has Ki values ranging from 61 to 543 nM for CB1 receptors and from 279 to 1,940 nM for...
| Keywords: | AEA, Anandamide, N-(2-hydroxyethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide |
| Application: | Bioactive Lipid assays |
| CAS | 94421-68-8 |
| MW: | 347.5 D |
From 70.00€
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Item number: Cay21130-1
(-)-Altenuene is a natural mycotoxin that was first isolated from A. tenuis. It has antioxidant activity and inhibits cholinesterases. Unlike tenuazonic acid (Cay-11443), (-)-altenuene does not display toxicity as assessed by the chicken embryo assay. (-)-Altenuene does not display significant topoisomerase...
| Keywords: | 2R,3R,4aR,4a-tetrahydro-2,3,7-trihydroxy-9-methoxy-4a-methyl-6H-dibenzo[b,d]pyran-6-one |
| Application: | Mycotoxin, antioxidant, cholinesterase inhibitor |
| CAS | 889101-41-1 |
| MW: | 292.3 D |
1,253.00€
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Item number: AG-CN2-0010-M001
Most commonly-used phorbol ester, Binds to and activates protein kinase C (PKC) at nM concentrations, Induces cell growth arrest through a variety of pathways including the mitogen-activated protein kinases (MAPKs), p38 and c-Jun N-terminal kinase (JNK) pathways mediated by cyclin dependent kinase (CDK) inhibitors...
| Keywords: | PMA, TPA, 12-O-Tetradecanoylphorbol 13-acetate |
| Application: | PKC activator |
| CAS | 16561-29-8 |
| MW: | 616,8 D |
From 44.00€
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Item number: 01503.25
Crystalline, H2O: <2%, It is effective against gram-positive and some gram-negative bacteria, inhibiting cell wall synthesis.
| Application: | Antibiotic |
| CAS | 69-52-3 |
| MW: | 371.39 |
68.00€
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Item number: ABD-21048
Ex: 458 nm. Em: 597 nm. Soluble in: DMSO. Fura Red is a visible light-excitable fura-2 analog that offers unique possibilities for ratiometric measurement of calcium ion in single cells by microphotometry, imaging or flow cytometry when used with single excitation, green-fluorescent calcium indicators. Fura Red AM...
| Application: | Cell-permeable ratiometric fluorescent calcium indicator, Fura-2 analog, FC, Single cell imaging |
| CAS | 149732-62-7 |
| MW: | 1089 D |
From 363.00€
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Item number: Cay11442-1
Tentoxin is a cyclic tetrapeptide first isolated from the plant pathogen A. alternata. It is an herbicide that inhibits chloroplast development, resulting in chlorotic tissue. Tentoxin is selectively phytotoxic, as it kills a number of important weeds at concentrations that have no effects on several important...
| Keywords: | cyclo[N-methyl-L-alanyl-L-leucyl-(alphaZ)-alpha,beta-didehydro-N-methylphenylalanylglycyl] |
| Application: | Herbicide, chloroplast development inhibitor |
| CAS | 28540-82-1 |
| MW: | 414.5 D |
From 296.00€
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Item number: Cay16751-100
Biocytin is a conjugate of biotin and lysine known formally as ?-N-(d-biotinyl)-L-lysine. The addition of lysine to biotin increases the chain length extending from biotin, allowing the synthesis of medium-chain reagents. It also provides terminal carboxyl and amino groups for derivatization or conjugation to...
| Keywords: | e-N-(d-Biotinyl)-L-lysine, N6-[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]-L-lysine |
| Application: | Neuroanatomical tracer |
| CAS | 576-19-2 |
| MW: | 372.5 D |
From 58.00€
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