No results were found for the filter!
ODN 1668 (Type B) Endotoxin-free (sterile)
Item number: IAX-200-001-M001
3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 1720 (Cat. No.: IAX-200-200).
| Keywords: | CpG ODN TLR9 Agonist: B Type (species: rodent) |
| Application: | TLR9 activator |
| MW: | 6383 D |
From 191.00€
*
Amphotericin B (Fungizone) Solution, 100X
Item number: A2230.100
Amphotericin B is a polyene antifungal agent for yeast, mold and mycoplasma. It was first isolated by Gold, et a., from Streptomyces nodosus in 1955. It is an amphoteric compound composed of a hydrophilic polyhydroxyl chain along one side and a lipophilic polyene hydrocarbon chain on the other. Amphotericin B is...
| CAS | 1397-89-3 |
| MW: | 924.09 D |
From 102.00€
*
Isopropyl-beta-D-thiogalacto- pyranoside (IPTG)
Item number: 05684.25
Purity: >99%. Free of dioxane and other solvents. For use im molecular biology. In combination with X-Gal (cat# 02249) it is used to detect lac+ colonies in cloning experiments.
| Application: | Inducer of beta-galactosidase |
| CAS | 367-93-1 |
| MW: | 238.30 |
From 128.00€
*
D-Luciferin, sodium salt *UltraPure Grade*
Item number: ABD-12511
Luciferin is the most popular and versatile bioluminescent substrate.
| Application: | Bioluminescence assays |
| CAS | 103404-75-7 |
From 114.00€
*
BMS309403
Item number: Cay10010206-5
Fatty acid binding protein 4 (FABP4) is a lipid transport protein that is also known as adipocyte FABP and aP2. In addition to adipocytes, it is also abundant in macrophages, along with FABP5, the epidermal FABP. BMS309403 is a cell-permeable, potent inhibitor of FABP4 that targets the fatty acid-binding pocket (Ki...
| Keywords: | A-FABP Inhibitor, Adipocyte FABP Inhibitor, ALBP Inhibitor, aP2 Inhibitor, FABP4 Inhibitor, Fatty Acid Binding Protein 4... |
| Application: | Cell-permeable, potent FABP4 inhibitor |
| CAS | 300657-03-8 |
| MW: | 474.6 D |
From 69.00€
*
SAG
Item number: Cay11914-1
Smoothened agonist (SAG) is a chlorobenzothiophene-containing compound which acts as a SMO agonist (EC50 = 3 nM) but inhibits hedgehog signaling at high concentrations (>1 µM). It directly binds to SMO and can block SMO inhibition by cyclopamine. Binding of SAG alters the conformation of SMO, leading to its...
| Keywords: | Smoothened Agonist,... |
| Application: | Smo Agonist |
| CAS | 912545-86-9 |
| MW: | 490.1 D |
From 42.00€
*
Prostaglandin E1
Item number: Cay13010-1
Prostaglandin E1 (PGE1) is a vasoactive prostaglandin and an active metabolite of dihomo-gamma-linolenic acid (DGLA, Cay-90230). It is formed from DGLA by COX-1 and COX-2. PGE1 is an agonist of the PGE2 (Cay-14010) receptor subtypes EP1, EP2, EP3, and EP4, and the IP receptor (Kis = 36, 10, 1.1, 2.1, and 33 nM,...
| Keywords: | Alprostadil, PGE1, 9-oxo-11alpha,15S-dihydroxy-prost-13E-en-1-oic acid |
| Application: | Bioactive lipid assays |
| CAS | 745-65-3 |
| MW: | 354.5 D |
From 45.00€
*
Tamoxifen
Item number: Cay13258-1
Tamoxifen is an estrogen receptor antagonist (IC50 = 45 nM for the rabbit receptor). It reduces the proliferation of MCF-7 breast cancer cells when used at a concentration of 10 µM. Tamoxifen is active against S. cerevisiae, C. neoformans, and five Candida species (MICs = 12, 64, and 8-64 µg/ml, respectively). It...
| Keywords: | 2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-ethanamine |
| Application: | Estrogen receptor modulator |
| CAS | 10540-29-1 |
| MW: | 371.5 D |
From 101.00€
*
15-keto Prostaglandin E1
Item number: Cay13680-1
15-keto PGE1 is the inactive metabolite of PGE1 produced by 15-hydroxy PGDH. It has greatly diminished biological activity compared to PGE1.Formal Name: (11alpha,13E)-11-hydroxy-9,15-dioxo-prost-13-en-1-oic acid. CAS Number: 22973-19-9. Synonyms: 15-keto PGE1. Molecular Formula: C20H32O5. Formula Weight: 352.5....
| Keywords: | 15-keto PGE1, 9,15-dioxo-11alpha-hydroxy-prost-13E-en-1-oic acid |
| Application: | Bioactive lipid assays |
| CAS | 22973-19-9 |
| MW: | 352.5 D |
From 101.00€
*
Prostaglandin I2 (sodium salt)
Item number: Cay18220-1
Prostaglandin I2 (PGI2) is an unstable cyclooxygenase metabolite detected first in vascular endothelial cells. It elevates platelet cAMP and is a potent vasodilator and inhibitor of human platelet aggregation with an IC50 of 5 nM. PGI2 is stable in basic buffers (pH=8), but it is rapidly hydrolyzed to 6-keto...
| Keywords: | Epoprostenol, PGI2, Prostacyclin, 6,9alpha-epoxy-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid, monosodium salt |
| Application: | Bioactive lipid assays |
| CAS | 61849-14-7 |
| MW: | 374.5 D |
From 122.00€
*
Arachidonic Acid-d8
Item number: Cay390010-1
Arachidonic acid-d8 is intended for use as an internal standard for the quantification of arachidonic acid (Cay-90010) by GC- or LC-MS. Arachidonic acid is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes. Virtually all cellular arachidonic acid is esterified in membrane...
| Keywords: | AA-d8, 5Z,8Z,11Z,14Z-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid |
| Application: | Standard |
| CAS | 69254-37-1 |
| MW: | 312.5 D |
From 198.00€
*
(±)11(12)-EET
Item number: Cay50511-50
(±)11(12)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid (Cay-90010) by cytochrome P450 enzymes. A higher proportion of 11(R),12(S)-EET is produced by the CYP450 isoforms CYP2C23 and CYP2C24 while CYP2B2 produces a higher proportion of 11(S),12(R)-EET. 11(12)-EET...
| Keywords: | (±)11,12-EpETrE, (±)11,(12)-epoxy-5Z,8Z,14Z-eicosatrienoic acid |
| Application: | Bioactive lipid assays |
| CAS | 87173-81-7 |
| MW: | 320.5 D |
From 91.00€
*