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Sanguinarine (chloride)
Item number: Cay16951-10
Sanguinarine is a benzylisoquinoline alkaloid isolated from plants belonging to the family Papaveraceae. It exhibits antimicrobial, anti-inflammatory, and anti-oxidant properties and demonstrates antiproliferative and pro-apoptotic effects in some cancer cell lines. Sanguinarine suppresses NF-kappaB activation by...
| Keywords: | 13-methyl-[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium, monochloride |
| Application: | Benzylisoquinoline alkaloid |
| CAS | 5578-73-4 |
| MW: | 367.78 D |
From 51.00€
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Urea, ultra pure
Item number: 50250.1
Purity: >=99.5%. Suitable for electrophoresis
| Application: | Denaturing agent |
| CAS | 57-13-6 |
| MW: | 60.06 |
46.00€
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Ferrostatin-1
Item number: Cay17729-5
Ferrostatin-1 is a ferroptosis inhibitor. It inhibits cell death induced by the ferroptosis inducers erastin (Cay-17754, EC50 = 60 nM) and RSL3, but not by hydrogen peroxide, rotenone, or staurosporine, in HT-1080 cells when used at a concentration of 0.5 µM. Ferrostatin-1 (0.5 µM) inhibits erastin-induced...
| Keywords: | Fer-1, 3-amino-4-(cyclohexylamino)-benzoic acid, ethyl ester |
| Application: | Ferroptosis inhibitor |
| CAS | 347174-05-4 |
| MW: | 262.4 D |
From 85.00€
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D-Luciferin, potassium salt *UltraPure Grade*
Item number: ABD-12506
Luciferin is the most popular and versatile bioluminescent substrate.
| Application: | Bioluminescence assays |
| CAS | 115144-35-9 |
From 114.00€
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(+)-JQ1
Item number: Cay11187-5
The bromodomain and extra terminal domain (BET) family of proteins, including BRD2, BRD3, and BRD4, play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes. JQ1 displaces...
| Keywords: | (6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid,... |
| Application: | BRD4 inhibitor |
| CAS | 1268524-70-4 |
| MW: | 457 D |
From 44.00€
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Bleomycin (sulfate)
Item number: Cay13877-10
Bleomycin is a glycopeptide antitumor antibiotic produced by the bacterium S. verticillus. Its mechanism of action causes single- and double-strand DNA breaks in tumor cells, which interrupts the cell cycle. Bleomycin is thought to achieve this by chelating metal ions, producing a pseudoenzyme that reacts with...
| Keywords: | Blenoxane, bleomycin sulfate (salt) |
| Application: | Apoptosis inducer |
| CAS | 9041-93-4 |
| MW: | 1415.6 D |
From 55.00€
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PAF C-16
Item number: Cay60900-5
PAF C-16 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the "remodeling" and 'de novo' pathways. It is a potent mediator of neutrophil migration, and the production of reactive oxygen species, and IL-6 in human macrophages. It is a more potent mediator of...
| Keywords: | Platelet-activating Factor C-16, 1-O-hexadecyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine |
| Application: | Bioactive lipid assays |
| CAS | 74389-68-7 |
| MW: | 523.7 D |
From 57.00€
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Nigericin, sodium salt
Item number: AG-CN2-0020-M005
Isolated from Streptomyces hygroscopicus. Antibiotic. High affinity ionophore for monovalent cations such as H, K, Na, Pb2. Shows antibacterial (Gram-positive), antifungal, antitumor and antiviral activity. Disrupts membrane potential and Golgi apparatus in mitochondria. NLRP3/NALP3 activator. Signals through...
| Keywords: | Antibiotic K 178, Helexin C, Polyetherin A, BRN 1696755, Azalomycin M, Antibiotic X-464 |
| Application: | Ionophore |
| CAS | 28643-80-3 |
From 72.00€
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Piericidin A
Item number: Cay15379-5
Complex I, also known as NADH:ubiquinone oxidoreductase or NADH dehydrogenase (ubiquinone), catalyzes the transfer of electrons from NADH to ubiquinone (also known as coenzyme Q10) as part of the respiratory chain leading to ATP generation. Piericidin A is an irreversible inhibitor of mitochondrial complex I that...
| Keywords: | AR 054, Shaoguanmycin B, SN 198E,... |
| Application: | Mitochondrial Complex I inhibitor |
| CAS | 2738-64-9 |
| MW: | 415.6 D |
From 230.00€
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DABCYL acid (4-((4-(Dimethylamino)phenyl)azo)benzoic...
Item number: ABD-2001
DABCYL acid is one of the most popular acceptors for developing FRET-based nucleic acid probes suh as Molecular Beacon-based PCR probes. It is predominantly paired with EDANS (as fluorescence donor) in FRET-based fluorescent probes.
| Application: | Labeling |
| CAS | 6268-49-1 |
218.00€
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Carmustine
Item number: LKT-C0173.100
Carmustine is an antitumor agent.
| Keywords: | BCNU, bis-chloroethylnitrosourea |
| Application: | Anticancer agent |
| CAS | 154-93-8 |
| MW: | 214,05 D |
From 104.00€
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NADP+, disodium salt
Item number: 62263.1
Assay: >85% enzymatically
| Keywords: | beta-Nicotinamide-adenine-dinucleotide phosphate Na2-salt |
| CAS | 24292-60-2 |
| MW: | 787.40 D |
From 259.00€
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