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(1S,3R)-RSL3
Item number: Cay19288-5
(1S,3R)-RSL3 is a ferroptosis inducer and is canonically known as an inhibitor of glutathione peroxidase 4 (GPX4). It inhibits GPX4 in a context-dependent manner: (1S,3R)-RSL3 inhibits GPX4 in the presence of cell cytosol or recombinant human 14-3-3epsilon, an adaptor protein, but does not inhibit recombinant human...
| Keywords: | (1S,3R)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-[4-(methoxycarbonyl)phenyl]-1H-pyrido[3,4-b]indole-3-carboxylic acid,... |
| Application: | GPX4 inhibitor |
| CAS | 1219810-16-8 |
| MW: | 440.9 D |
From 55.00€
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Biotinyl tyramide
Item number: CDX-B0270-M100
White to light pink solid. Soluble in acetonitrile. Biotin derivative. Substrate of the horseradish peroxidase enzyme and used as a reagent to amplify immunohistochemical signals. It is based on the HRP-catalyzed deposition of tyramide conjugates (such as biotinyl-tyramide) on a solid phase. Subsequent reaction with...
| Keywords: | Biotin-Phenol, BP, N-(4-Hydroxyphenethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide |
| Application: | Biotin derivative, HRP substrate, IHC signal amplifier |
| CAS | 41994-02-9 |
| MW: | 363,5 D |
From 199.00€
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Beauvericin
Item number: Cay11426-1
Beauvericin is a mycotoxin originally derived from B. bassiana, a common fungal parasite of arthropods. It is also produced by the fungus Fusarium, a pathogen of insects and plants. Beauvericin is cytotoxic against insect cells, killing the insect cell line SF-9 with a 50% cytotoxic concentration of 2.5 µM. In...
| Keywords: | cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl-(2R)... |
| Application: | Mycotoxin, Apoptosis inducer |
| CAS | 26048-05-5 |
| MW: | 784 D |
From 55.00€
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12(S)-HETE
Item number: Cay34570-25
12(S)-HETE is the predominant lipoxygenase product of mammalian platelets. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 µM.Formal Name: 12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid. CAS Number: 54397-83-0. Synonyms: 12(S)-Hydroxyeicosatetraenoic Acid....
| Keywords: | 12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 54397-83-0 |
| MW: | 320.5 D |
From 229.00€
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Calbryte(TM)-590 AM
Item number: ABD-20702
Ex: 573 nm. Em: 588 nm. Soluble in: DMSO. The intracellular calcium flux assay is a widely used method in monitoring signal transduction pathways and high throughput screening of G protein-coupled receptors (GPCRs) and calcium channel targets. Followed by Rhod-2 being introduced in 1989, Rhod-4 and Cal-590 were...
| Application: | FC |
| MW: | 1218,77 D |
From 291.00€
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Purmorphamine
Item number: Cay10009634-10
Small molecules that promote osteoblast differentiation might be useful as therapeutic agents for bone diseases such as osteoporosis. Purmorphamine is a 2,6,9-trisubstituted purine that promotes the differentiation of both human and mouse mesenchymal progenitor cells into osteoblasts. The EC50 value for...
| Keywords: | 9-cyclohexyl-N-[4-(morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine |
| Application: | Differentiation promotor |
| CAS | 483367-10-8 |
| MW: | 520.6 D |
From 55.00€
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MAHMA NONOate
Item number: Cay82130-10
MAHMA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 1 minute and 3 minutes at 37°C and 22-25°C, respectively, (pH 7.4) to liberate 2 moles of NO per mole of parent compound.Formal Name:...
| Keywords: | Methylamine hexamethylene methylamine NONOate, (Z)-1-[N-Methyl-N-[6-(N-methylammoniohexyl)amino]]diazen-1-ium-1,2-diolate |
| Application: | NO donor |
| CAS | 146724-86-9 |
| MW: | 204.3 D |
From 59.00€
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Doxycycline Hyclate
Item number: LKT-D5897.25
An antimicrobial agent. Used in the treatment of severe purulent inflammatory diseases such as pneumonia, lung abscesses, pyothorax, skin and soft tissue infections, peritonitis, purulent cholangitis and others
| Application: | Antimicrobial agent |
| CAS | 24390-14-5 |
| MW: | 512,9 D |
From 57.00€
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DEA NONOate
Item number: Cay82100-10
DEA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 2 minutes and 16 minutes at 37°C and 22-25°C, pH 7.4, respectively, to liberate 1.5 moles of NO per mole of parent compound.Formal Name: Diethylammonium (Z)-1-(N,N-diethylamino)diazen-1-ium-1,2-diolate....
| Keywords: | DEA/NO, Diethylamine NONOate, Diethylammonium (Z)-1-(N,N-diethylamino)diazen-1-ium-1,2-diolate |
| Application: | NO donor |
| CAS | 372965-00-9 |
| MW: | 206.3 D |
From 55.00€
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Dihomo-gamma-Linolenic Acid
Item number: Cay90230-10
Dihomo-gamma-Linolenic Acid (DGLA, 20:3), an elongation product of gamma-linolenic acid (18:3), is rapidly metabolized by fatty acid desaturases to produce arachidonic acid (20:4). DGLA is metabolized through the cyclooxygenase pathway to produce 1-series prostaglandins, including PGE1. In mice, DGLA supplementation...
| Keywords: | cis-8,11,14-Eicosatrienoic Acid, DGLA, gamma-Homolinolenic Acid, 8Z,11Z,14Z-eicosatrienoic acid |
| Application: | LTB4 receptor antagonist |
| CAS | 1783-84-2 |
| MW: | 306.5 D |
From 55.00€
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(±)12(13)-DiHOME
Item number: Cay10009832-100
(±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME (Cay-52450), a cytochrome P450-derived epoxide of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) also known as isoleukotoxin. It is formed from 12(13)-EpOME by soluble epoxide hydrolase (sEH) in neutrophils. 12(13)-DiHOME is toxic to Sf21 cells expressing sEH...
| Keywords: | Isoleukotoxin diol, 12,13-dihydroxy-9Z-octadecenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 263399-35-5 |
| MW: | 314.5 D |
From 70.00€
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Dihydroethidium
Item number: Cay12013-5
Dihydroethidium is a cell-permeable blue fluorescent dye that upon entering cells interacts with superoxide to form oxyethidium, which intercalates with nucleic acids and emits a red fluorescence detectable qualitatively by fluorescent microscopy or quantitatively by HPLC. It displays excitation/emission spectra of...
| Keywords: | Hydroethidine, PD-MY 003, 5-ethyl-5,6-dihydro-6-phenyl-3,8-phenanthridinediamine |
| Application: | Fluorescent dye, reactive oxygen detection |
| CAS | 104821-25-2 |
| MW: | 315.4 D |
From 74.00€
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