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Nigericin (sodium salt)
Item number: Cay11437-5
Nigericin is a lipophilic potassium ionophore that has been found in S. hygroscopicus. It mediates neutral antiport of potassium and proton ions across mitochondrial membranes. Nigericin (10 µM) induces T. gondii egress in infected human foreskin fibroblasts (HFFs). It also induces NOD-like receptor protein 3...
| Keywords: | NSC 292567,... |
| Application: | Metabolic studies |
| CAS | 28643-80-3 |
| MW: | 747 D |
From 101.00€
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2-Hydroxypropyl-beta-cyclodextrin
Item number: Cay16169-25
2-Hydroxypropyl-beta-cyclodextrin (HP-beta-CD) is a cyclic oligosaccharide containing seven D-(+)-glucopyranose units that is widely used to improve the aqueous solubility of various compounds, especially those containing a phenyl group. The circular arrangement of its glucose units produces a torus-shaped ring...
| Keywords: | HP-beta-CD, 2-hydroxypropyl ethers beta-cyclodextrin |
| Application: | Solubility enhancer |
| CAS | 128446-35-5 |
| MW: | 1541.6 D |
From 60.00€
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Oleic Acid
Item number: Cay90260-500
Oleic acid is a monounsaturated fatty acid and a major component of membrane phospholipids that has been found in human plasma, cell membranes, and adipose tissue. It contributes approximately 17% of the total fatty acids esterified to phosphatidylcholine, the major phospholipid class in porcine platelets. Oleic...
| Keywords: | cis-9-Octadecenoic acid, 9Z-octadecenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 112-80-1 |
| MW: | 282.5 D |
From 40.00€
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Resolvin E1
Item number: Cay10007848-10
Resolvin E1 (RvE1) is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids. It is produced from eicosapentaenoic acid (EPA, Cay-90110, Cay-90110.1, Cay-21908) via an 18-HEPE epoxide intermediate, which is formed by aspirin-acetylated COX-2-mediated oxidation of EPA and 5-lipoxygenase...
| Keywords: | RvE1, 5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 552830-51-0 |
| MW: | 350.5 D |
From 214.00€
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Anhydrotetracycline (hydrochloride)
Item number: Cay10009542-50
The tetracycline repressor (TetR) is a transcriptional regulator which normally binds tightly to its palindromic tetO operator DNA, blocking gene expression. Tet causes the repressor to dissociate from the DNA, allowing transcription to occur. A novel reverse TetR (revTetR) requires tetracycline as a co-repressor to...
| Keywords: | 4-(dimethylamino)-1,4S,4aS,5,12,12aS-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide,... |
| Application: | Antibiotic |
| CAS | 13803-65-1 |
| MW: | 462.9 D |
From 76.00€
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C11 BODIPY 581/591
Item number: Cay27086-1
C11 BODIPY 581/591 is a lipid-soluble ratiometric fluorescent indicator of lipid oxidation. Upon oxidation, its excitation maximum shifts from 581 to 500 nm and the emission maximum shifts from 591 to 510 nm. C11 BODIPY 581/591 has been used in the quantitation of ferroptosis.Formal Name:...
| Keywords: | (T-4)-difluoro[5-[[5-[(1E,3E)-4-phenyl-1,3-butadien-1-yl]-2H-pyrrol-2-ylidene-kappaN]methyl]-1H-pyrrole-2-undecanoato(2-)-... |
| Application: | Lipid-soluble ratiometric fluorescent lipid oxidation indicator |
| CAS | 217075-36-0 |
| MW: | 504.4 D |
230.00€
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BCIP, p-toluidine salt
Item number: 02291.1
Soluble in DMF, hardly soluble in water. Use as alkaline phosphatase substrate forming a water insoluble blue reaction product. Often used together with NBT (Art.-Nr. 06428) for immunocytochemistry.
| Application: | Substrate for alkaline phosphatase |
| CAS | 6578-06-9 |
| MW: | 433.60 |
From 87.00€
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LY379268
Item number: Cay15351-10
LY379268 is a potent, brain-permeable, and selective agonist of group II metabotropic glutamate receptors (mGluRs), subtypes mGluR2 and mGluR3. In an assay of second messenger response, LY379268 exhibits EC50 values of 2.69 and 4.48 nM for human mGluR2 and mGluR3, respectively, with at least 80-fold selectivity over...
| Keywords: | (1R,4R,5S,6R)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid |
| Application: | mGluR2 / mGluR3 agonist |
| CAS | 191471-52-0 |
| MW: | 187.2 D |
From 78.00€
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Tryptamine hydrochloride
Item number: TGM-T124997-10g
Description: Tryptamine hydrochloride is a monoamine alkaloid, metabolite of tryptophan and CNS active substance, agonist of 5-HT4 receptor, TAAR1 and AHR, with potential for blood-brain barrier permeability. Target: Endogenous Metabolite, 5-HT Receptor, AhR. Smiles: Cl.NCCC1=CNC=2C=CC=CC21
| Keywords: | 3-(2-Aminoethyl)indole~2-(3-Indolyl)ethylamine HCl |
| MW: | 196.68 D |
From 29.00€
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Thromboxane B2
Item number: Cay19030-1
Thromboxane B2 (TXB2) is a non-enzymatically derived, stable, inactive metabolite of TXA2, which is highly unstable. Serum levels of TXB2 positively correlate with platelet COX-1 activation. Urinary levels of TXB2 reflect intrarenal TXA2 synthesis, while its metabolites, 11-dehydro TXB2 (Cay-19500) and 2,3-dinor...
| Keywords: | TXB2, 9alpha,11,15S-trihydroxythromba-5Z,13E-dien-1-oic acid |
| Application: | Bioactive lipid assays |
| CAS | 54397-85-2 |
| MW: | 370.5 D |
From 147.00€
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Leukotriene B4-d4
Item number: Cay320110-25
Leukotriene B4-d4 (LTB4-d4) is intended for use as an internal standard for the quantification of LTB4 (Cay-20110) by GC- or LC-MS. LTB4 is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway. It promotes a number of leukocyte functions including aggregation, stimulation of ion...
| Keywords: | LTB4-d4, 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraenoic-6,7,14,15-d4 acid |
| Application: | Standard |
| CAS | 124629-74-9 |
| MW: | 340.5 D |
466.00€
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NG,NG-dimethyl-L-Arginine (hydrochloride)
Item number: Cay80230-50
NG,NG-dimethyl-L-arginine (ADMA) is an endogenous inhibitor of nitric oxide synthase (NOS). It is formed from arginine by protein arginine methyltransferases (PRMTs) and degraded by dimethylarginine dimethylaminohydrolases (DDAHs) and alanine-glyoxylate aminotransferase 2 (AGXT2). ADMA levels are increased...
| Keywords: | ADMA, Asymmetric dimethylarginine, N5-[(dimethylamino)iminomethyl]-L-ornithine, dihydrochloride |
| Application: | NOS inhibitor |
| CAS | 220805-22-1 |
| MW: | 275.2 D |
From 40.00€
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