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RIP1 kinase inhibitor 6
Item number: TGM-T79043-100mg
Description: RIP1 Kinase Inhibitor 6 is a potent and selective inhibitor of RIP1 kinase, demonstrating inhibitory activity with an IC50 of less than 100 nM in a human R1P1 kinase assay[1]. Target: RIP kinase
| Application: | RIP1 kinase inhibitor |
| CAS | 2428401-62-9 |
| MW: | 360.35 D |
From 1,440.00€
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RIP1 kinase inhibitor 7
Item number: TGM-T79044-100mg
Description: RIP1 Kinase Inhibitor 7 (Compound 41) serves as a potent inhibitory agent for receptor interacting protein 1 kinase (RIP1) with an IC50 of under 100 nM. Additionally, it demonstrates an EC50 ranging from 1 to 100 nM in cell necrosis assays [1]. Target: RIP kinase
| Application: | RIP1 kinase inhibitor |
| CAS | 2428401-23-2 |
| MW: | 337.39 D |
From 1,440.00€
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AXL-IN-15
Item number: TGM-T79045-50mg
Description: AXL-IN-15 (cpd391) is a potent Axl inhibitor with a dissociation constant (K i) and half-maximal inhibitory concentration (IC50) of less than 1 nanomolar (nM), suitable for cancer research [1]. Target: TAM Receptor
| CAS | 1954722-22-5 |
| MW: | 575.59 D |
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CDK4-IN-2
Item number: TGM-T79046-50mg
Description: CDK4-IN-2 (A17) is a potent CDK4 inhibitor with K i and IC 50 values below 10 nM, used in cancer research [1]. Target: CDK
| CAS | 2380320-68-1 |
| MW: | 508.54 D |
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MEK-IN-6
Item number: TGM-T79047-100mg
Description: MEK-IN-6 (Example 69), a potent MEK inhibitor, effectively inhibits ERK1/2 (Thr202/Tyr204) phosphorylation in A375 cells, with an IC50 of 2 nM, making it valuable for cancer research [1]. Target: ERK
| CAS | 2845151-86-0 |
| MW: | 393.43 D |
From 1,583.00€
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MEK-IN-6 hydrate
Item number: TGM-T79048-100mg
Description: MEK-IN-6 hydrate (compound 69), a MEK inhibitor, exhibits an IC50 value of 2 nM in A375 cells [1]. Target: MEK
| CAS | 2845153-35-5 |
| MW: | 411.45 D |
From 1,583.00€
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Tegeprotafib
Item number: TGM-T79049-25mg
Description: Tegeprotafib (PTPN2/1-IN-1, Compound 124) is an orally active inhibitor targeting both PTPN2 and PTPN1B, with potent IC50 values of 4.4 nM for PTPN2 and 1-10 nM for PTPN1B, respectively [1]. Target: Phosphatase. Smiles: O=C1NS(=O)(=O)N(C=2C(O)=CC3=CC=C(OC)C=C3C2F)C1
| Keywords: | PTPN2/1-IN-1 |
| CAS | 2407610-46-0 |
| MW: | 326.3 D |
From 1,848.00€
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JBI-589
Item number: TGM-T79050-50mg
Description: JBI-589 is an isoform-selective, non-covalent inhibitor of PAD4 that diminishes CXCR2 expression and impedes neutrophil chemotaxis. Additionally, it attenuates primary tumor growth and metastases, augmenting the efficacy of checkpoint inhibitors [1]. Target: Others
| CAS | 2308504-22-3 |
| MW: | 481.56 D |
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PCSK9-IN-15
Item number: TGM-T79051-50mg
Description: PCSK9-IN-15 (compound 5) is a potent inhibitor of proprotein convertase subtilisin/kexin 9 (PCSK9, K D <200 nM) that plays a crucial role in cholesterol metabolism by regulating blood levels of low-density lipoprotein cholesterol (LDL-C). This compound is useful for researching cholesterol-lowering...
| CAS | 2455423-94-4 |
| MW: | 472.63 D |
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PCSK9-IN-16
Item number: TGM-T79052-100mg
Description: PCSK9-IN-16, holds potential for research into hypercholesterolemia and other cardiovascular diseases [1]. Target: Others
| CAS | 2455424-51-6 |
| MW: | 424.56 D |
From 2,295.00€
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PCSK9-IN-17
Item number: TGM-T79053-100mg
Description: PCSK9-IN-17 is a PCSK9 inhibitor employed in cholesterol metabolism research. Target: Others
| CAS | 2455424-72-1 |
| MW: | 329.42 D |
From 2,295.00€
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TRPC3/6-IN-2
Item number: TGM-T79054-50mg
Description: TRPC3/6-IN-2 is a potent inhibitor of TRPC3 and TRPC6, with IC50 values of 16 nM and 29.8 nM, respectively [1]. Target: Others
| CAS | 2387893-55-0 |
| MW: | 347.41 D |
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