No results were found for the filter!
HPK1-IN-39
Item number: TGM-T78852-50mg
Description: HPK1-IN-39 (Compound 10n), a selective inhibitor of Hematopoietic Progenitor Kinase 1 (HPK1) with an inhibitory concentration (IC50) of 29 nM, impedes the phosphorylation of SLP76. This compound is applicable in the research of cancer immunotherapy [1]. Target: Others
| MW: | 469.54 D |
Please request pricing for this article.
PI3K-IN-47
Item number: TGM-T78853-50mg
Description: PI3K-IN-47 (Compound 27) is a potent bivalent inhibitor targeting the phosphoinositide 3-kinases (PI3K) family, with IC50 values of 0.44 nM for PI3Kalpha, and 7.18 nM, 13.92 nM, and 22.83 nM for PI3Kbeta, PI3Kgamma, and PI3Kdelta respectively. It induces G1 phase cell cycle arrest and exhibits...
| MW: | 1027.07 D |
Please request pricing for this article.
WK499
Item number: TGM-T78854-50mg
Description: BCL6-IN-10 (Compound WK499) is an inhibitor of BCL6 that disrupts its interaction with the SMRT protein, promoting apoptosis, cell cycle arrest, and DNA damage. It effectively hampers the proliferation of various AML cell lines, with IC50 values of 0.91, 1.63, 1.026, 7.42, 0.87, and 0.85 µM for...
| MW: | 498.33 D |
Please request pricing for this article.
Anticancer agent 157
Item number: TGM-T78855-50mg
Description: Anticancer Agent 157 (compound 15) is a nitric oxide (NO) inhibitor with IC50 values of 0.62 µg/mL, exhibiting both anti-inflammatory and anticancer effects. It interacts with inducible NO synthase (iNOS) and caspase 8, which facilitates apoptosis through nuclear fragmentation and chromatin...
| MW: | 220.31 D |
Please request pricing for this article.
Biotin-labeled ODN 1018 sodium
Item number: TGM-T78990-50mg
Description: Biotin-labeled ODN 1018 (sodium), a TLR-9 agonist oligodeoxynucleotide, is used to evaluate cellular uptake and localization of CpG ODNs via biotin detection systems and light microscopy. Target: Others
Please request pricing for this article.
Biotin-labeled ODN 1585 sodium
Item number: TGM-T78991-50mg
Description: Biotin-labeled ODN 1585 (sodium) effectively induces IFN and TNFalpha production, and enables assessment of CpG ODN cellular uptake and localization via biotin system detection and light microscopy analysis. Target: Others
Please request pricing for this article.
FITC-labeled ODN 1585 sodium
Item number: TGM-T78992-50mg
Description: FITC-labeled ODN 1585 (sodium) effectively induces IFN and TNFalpha production and serves to assess CpG ODN cellular uptake and localization via confocal laser-scanning microscopy [excitation 495 nm, emission 520 nm] or flow cytometry. Target: Others
Please request pricing for this article.
Biotin-labeled ODN 1668 sodium
Item number: TGM-T78993-50mg
Description: Biotin-labeled ODN 1668 (sodium), a class B CpG oligodeoxynucleotide (ODN) and TLR9 agonist, enables the evaluation of cellular uptake and localization of CpG ODNs using a biotin detection system and light microscopy. Target: Others
Please request pricing for this article.
FITC-labeled ODN 1668 sodium
Item number: TGM-T78994-50mg
Description: FITC-labeled ODN 1668 (sodium), a class B CpG oligodeoxynucleotide (ODN), functions as a TLR9 agonist and is used to assess the cellular uptake and localization of CpG ODNs via confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) and flow cytometry. Target: Others
Please request pricing for this article.
Biotin-labeled ODN 2088 sodium
Item number: TGM-T78995-50mg
Description: Biotin-labeled ODN 2088 (sodium) is a potent inhibitor of TLR3, TLR7, and TLR9, used to evaluate cellular uptake and localization of CpG ODN via a biotin detection system in conjunction with light microscopy. Target: Others
Please request pricing for this article.
FITC-labeled ODN 2088 sodium
Item number: TGM-T78996-50mg
Description: FITC-labeled ODN 2088 (sodium) is a potent inhibitor of TLR3, TLR7, and TLR9, used to assess CpG ODN cellular uptake and localization via confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry. Target: Others
Please request pricing for this article.
Biotin-labeled ODN 2216 sodium
Item number: TGM-T78997-50mg
Description: Biotin-labeled ODN 2216 (sodium) acts as a specific agonist for human TLR9 (toll-like receptor 9), enabling the evaluation of CpG ODN cellular uptake and localization via a biotin detection system coupled with light microscopy. Target: Others
Please request pricing for this article.