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Carbenicillin, disodium salt
Item number: 50195.5
Carbenicillin is a bacteriolytic antibiotic belonging to the carboxypenicillin subgroup of the penicillins. It has Gram-negative coverage which includes Pseudomonas aeruginosa but limited Gram-positive coverage. The carboxypenicillins are susceptible to degradation by beta-lactamase enzymes, although they are more...
| Application: | Antibiotic |
| CAS | 4800-94-6 |
| MW: | 422.37 |
From 183.00€
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Resolvin D2
Item number: Cay10007279-10
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D2 (RvD2) is produced...
| Keywords: | 7(S),16(R),17(S)-Resolvin D2, RvD2, 7S,16R,17S-trihydroxy-4Z,8E,10Z,12E,14E,19Z-docosahexaenoic acid |
| Application: | Lipid mediator |
| CAS | 810668-37-2 |
| MW: | 376.5 D |
From 235.00€
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L-Buthionine-(S,R)-Sulfoximine
Item number: Cay14484-250
L-Buthionine-(S,R)-sulfoximine is an irreversible inhibitor of gamma-glutamylcysteine synthetase (Ki = 25 µM). It inhibits the proliferation of ZAZ and M14 melanoma cells, as well as A2780 ovarian and MCF-7 breast cancer cells (IC50s = 4.9, 18, 8.5, and 26.5 µM, respectively). L-Buthionine-(S,R)-sulfoximine (100µM)...
| Keywords: | BSO, NSC 326231, 2S-amino-4-(S-butylsulfonimidoyl)-butanoic acid |
| Application: | Oxidative stress inducer |
| CAS | 83730-53-4 |
| MW: | 222.3 D |
From 132.00€
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FTY720 Phosphate
Item number: Cay10008639-1
FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analog of sphingosine. It is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. In vivo, FTY720...
| Keywords: | FTY720P, 2-amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol, 1-(dihydrogen phosphate) |
| Application: | Sphingosine analog |
| CAS | 402615-91-2 |
| MW: | 387.5 D |
From 153.00€
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Cisplatin
Item number: Cay13119-50
Cisplatin is a platinum-containing compound that acts as a DNA-crosslinking agent and interferes with replication and transcription, culminating in apoptosis. It forms intra- and interstrand crosslinks with DNA with intrastrand guanine-to-guanine or guanine-to-alanine links accounting for the majority of DNA...
| Keywords: | cis-Diamminedichloroplatinum, CDDP, Cisplatinum, NSC 119875, (SP-4-2)-diamminedichloro-platinum |
| Application: | Alkylating agent, apoptosis inducer |
| CAS | 15663-27-1 |
| MW: | 300.1 D |
From 73.00€
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FMOC-Lys(5-FITC)-OH
Item number: ABD-5070
A building block for in-sequence Lys labeling by 5-FITC.
| Application: | Building block |
| CAS | 1095493-05-2 |
291.00€
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nor-NOHA (acetate)
Item number: Cay10006861-10
L-Arginine serves as a common substrate for both nitric oxide synthase (NOS) and arginase in the cell. NOS catalyzes the oxidation of arginine to citrulline and NO with Nomega-hydroxy-L-arginine (NOHA) formed as an intermediate. Arginase, on the other hand, catalyzes the hydrolysis of arginine into urea and...
| Keywords: | Nomega-hydroxy-nor-Arginine, 2S-amino-4-[[(hydroxyamino)iminomethyl]amino]-butanoic acid, diacetate |
| Application: | Arginase inhibitor |
| CAS | 1140844-63-8 |
| MW: | 296.3 D |
From 35.00€
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1-NA-PP1
Item number: Cay10954-10
1-NA-PP1 is a reversible, cell-permeable inhibitor of Src-family tyrosine kinases that have been mutated, by a single base substitution, to become 'analog sensitive' (as), as compared to the wild-type kinase. 1-NA-PP1 was first developed to optimally inhibit v-Src-as1, with an I338G substitution, preferentially over...
| Keywords: | 1-Naphthyl-PP1, PP1 Analog, 1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| CAS | 221243-82-9 |
| MW: | 317.4 D |
From 37.00€
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BAY 60-7550
Item number: Cay10011135-1
The second messengers cAMP and cGMP are important mediators of signal transduction and hence a wide range of cellular processes including vasodilation and synaptic plasticity. Type 2 cyclic nucleotide phosphodiesterases (PDE2) isoforms inactivate cAMP and cGMP by hydrolyzing the phosphodiester bond. BAY 60-7550 is a...
| Keywords: | 2-[(3,4-dimethoxyphenyl)methyl]-7-[(1R)-1-hydroxyethyl]-4-phenylbutyl]-5-methyl-imidazo[5,1-f][1,2,4]triazin-4(1H)-one |
| Application: | PDE2 inhibitor |
| CAS | 439083-90-6 |
| MW: | 476.6 D |
From 144.00€
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2-Arachidonoyl Glycerol
Item number: Cay62160-1
2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the cannabinoid (CB) receptors CB1 and CB2 (Kis = 25.3-472 and 145-1,400 nM, respectively). Unlike arachidonoyl ethanolamide (AEA, Cay-90050), 2-AG is present at relatively high levels in the central nervous system and is the most abundant molecular species...
| Keywords: | 2-AG, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 2-glyceryl ester |
| Application: | CB1 receptor agonist |
| CAS | 53847-30-6 |
| MW: | 378.6 D |
From 60.00€
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RatioWorks(TM) PDMPO
Item number: ABD-21204
The existing pH probes are ill-adapted to study acidic organelles such as lysosomes, endosomes, spermatozoa and acrosomes because their fluorescence is significantly reduced at lower pH. In addition, most of the existing pH probes (such as BCECF and SNARF) are not selectively localized in acidic organelles. The...
| Application: | Fluorescent pH indicator |
145.00€
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DiBAC4(3) (Bis-(1,3-dibutylbarbituric acid)trimethine...
Item number: ABD-21411
DiBAC4(5) is a sensitive membrane potential probe. Slow-response probes are suitable for detecting changes in average membrane potentials of nonexcitable cells.
| Application: | Membrane potential probe |
| CAS | 70363-83-6 |
145.00€
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