STAT3 mCherry Reporter Lentivirus

STAT3 mCherry Reporter Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. The particles contain an mCherry reporter under the control of the STAT3 (Signal Transducer and Activator of Transcription 3)-responsive element located upstream of the minimal TATA promoter. The lentiviruses also transduce a puromycin selection gene (Figure 1). After transduction, the activation of the STAT3 signaling pathway in the target cells can be monitored by examining mCherry expression. Figure 1. Schematic of the lenti-vector used to generate the STAT3 mCherry Reporter Lentivirus.