NF-qB mCherry Reporter Lentivirus

NF-?B mCherry Reporter Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. The particles contain an mCherry reporter under the control of the NF-kappaB (nuclear factor kappa-light chain enhancer of activated B cells) response element located upstream of the minimal TATA promoter. The lentiviruses also transduce a puromycin selection gene (Figure 1). After transduction, activation of the NF-kappaB signaling pathway in target cells can be monitored by assessing mCherry expression. Figure 1. Schematic of the lenti-vector used to generate the NF-?B mCherry Reporter Lentivirus.