AAV3 Luciferase

Item number Size Datasheet Manual SDS Delivery time Quantity Price
BPS-78454 100 µl (50 µl x 2) - -

3 - 15 business days*

819.00€
 
Adeno-Associated Virus Serotype 3 (AAV3) shares 82% sequence homology with AAV2, and like AAV2,... more
Product information "AAV3 Luciferase"
Adeno-Associated Virus Serotype 3 (AAV3) shares 82% sequence homology with AAV2, and like AAV2, requires the Heparan Sulfate Proteoglycan (HSPG) receptor for cell attachment. AAV3 vectors transduce human liver cancer cells extremely efficiently because AAV3 utilizes the human Hepatocyte Growth Factor Receptor (hHGFR) as a co-receptor for viral entry, which is highly expressed in these cells. Both the extracellular and intracellular kinase domains of hHGFR are required for AAV3-mediated transgene expression. These AAV particles constitutively express the firefly (Photinus pyralis) luciferase gene under the control of a CMV promoter. AAV transduction efficiency can easily be verified by measurement of luciferase activity.
Keywords: Luciferase, Luciferin 4-monooxygenase,
Supplier: BPS Bioscience
Supplier-Nr: 78454

Properties

Application: Positive transduction control, transduction assays optimization, temporal protein expression tracking
Species reactivity: human

Database Information

UniProt ID : P08659 | Matching products

Handling & Safety

Storage: -80°C
Shipping: -80°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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