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COVID-19 Research
Spike(SARS-CoV-2) Pseudotyped Lentivirus (Luc-eGFP Dual...
Item number: BPS-79982-1
The pandemic coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). As the first step of viral replication, the virus attaches to the host cell surface before entering the cell. The viral Spike protein recognizes and attaches to the Angiotensin-Converting...
| Keywords: | 2, |
| Application: | Viral transduction mechanism studies, SARS-CoV-2 Spike, ACE2 binding neutralizing antibody screening |
| Species reactivity: | SARS-CoV-2 |
From 1,599.00€
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COVID-19 Research
Bald Lentiviral Pseudovirion (eGFP Reporter)
Item number: BPS-79987
The bald lentiviral pseudovirion was produced without envelope glycoproteins such as VSV-G or SARS-CoV-2 spike. It contains the eGFP gene driven by a CMV promoter as the reporter. The bald lentiviral pseudovirion can serve as a negative control when studying virus entry initiated by specific interactions between...
| Keywords: | covid, covid-19, covid19, coronavirus, Severe acute respiratory Coronavirus Spike 2, pseudovirus, lentivirus, |
| Application: | Negative control pseudovirion, viral transduction mechanism studies |
1,248.00€
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COVID-19 Research
Bald Lentiviral Pseudovirion (Luc-eGFP Dual Reporter)
Item number: BPS-79988
The bald lentiviral pseudovirion was produced without envelope glycoproteins such as VSV-G or SARS-CoV-2 spike. It contains a firefly luciferase and eGFP cassette (Luc-P2A-eGFP) as the reporters, driven by a CMV promoter. The bald lentiviral pseudovirion can serve as a negative control when studying virus entry...
| Keywords: | covid, covid-19, covid19, coronavirus, Severe acute respiratory Coronavirus Spike 2, pseudovirus, pseudovirion,... |
| Application: | Negative control pseudovirion, viral transduction mechanism studies |
1,189.00€
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COVID-19 Research
Spike (SARS-CoV-2) Lentivirus
Item number: BPS-78010-1
Cell entry of SARS-CoV-2 depends on the binding of viral spike protein to cellular receptor ACE2. The SARS-CoV-2 Spike Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types mammalian cells, including primary and non-dividing...
| Keywords: | 2, |
| Application: | Transient knock-down, stable knock-out cell generation |
| Species reactivity: | SARS-CoV-2 |
From 1,307.00€
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COVID-19 Research
Spike (SARS-CoV-2, D614G) Pseudotyped Lentivirus (Luc...
Item number: BPS-78028-1
The pandemic coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). As the first step of the viral replication, the virus attaches to the host cell surface before entering the cell. The viral Spike protein recognizes and attaches to the Angiotensin-Converting...
| Keywords: | 2, |
| Application: | Viral transduction studies, neutralizing antibodies screening |
| Species reactivity: | SARS-CoV-2 |
From 1,343.00€
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PD-1 CRISPR/Cas9 Lentivirus (Integrating)
Item number: BPS-78052
The binding of Programmed Cell Death Protein 1 (PD-1), a receptor expressed on activated T-cells, to its ligands, PD-L1 and PD-L2, negatively regulates immune responses. PD-1 ligands are found on most cancers, and the PD-1:PD-L1/2 interaction inhibits T-cell activity and enables cancer cells to escape immune...
| Keywords: | SpCas9 lentivirus, CRISPR lentivirus, Cas9 lentivirus, Programmed Cell Death Protein 1 CRISPR, |
| Application: | Transient knock-down, stable knock-out cell generation |
| Species reactivity: | human |
1,285.00€
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LAG3 CRISPR/Cas9 Lentivirus (Integrating)
Item number: BPS-78053
Lymphocyte-activation gene 3 (LAG3, CD223) is a cell surface protein that belongs to the immunoglobulin (Ig) superfamily. LAG3 is expressed on activated T-cells, Natural Killer cells, B-cells, and plasmacytoid dendritic cells. Its main ligand is the MHC class II, to which it binds with higher affinity than CD4. It...
| Keywords: | Lymphocyte-activation gene 3 CRISPR, CD223 Lentivirus, |
| Application: | Transient knock-down, stable knock-out cell generation |
| Species reactivity: | human |
1,248.00€
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CTLA4 CRISPR/Cas9 Lentivirus (Integrating)
Item number: BPS-78054
CTLA4 (Cytotoxic T-Lymphocyte Associated Protein), also known as CD152, is a protein receptor that functions as an immune checkpoint. It is expressed by activated T-cells and transmits an inhibitory signal to T-cells. CTLA4 is homologous to the T-cell co-stimulatory protein CD28, and both molecules bind to CD80...
| Keywords: | Cytotoxic T-Lymphocyte Associated Protein Lentivirus, CD152 lentivirus, CTLA4 CRISPR, |
| Application: | Transient knock-down, stable knock-out cell generation |
| Species reactivity: | human |
1,248.00€
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TCR CRISPR/Cas9 Lentivirus (Integrating)
Item number: BPS-78055
The T-Cell Receptor (TCR) is found on the surface of T-cells and is responsible for recognizing antigens bound to MHC (Major Histocompatibility Complex) molecules. Activation of the TCR results in activation of downstream NFAT signaling. The TCR consists of a heterodimer of two different protein chains, of which the...
| Keywords: | SpCas9 lentivirus, CRISPR lentivirus, Cas9 lentivirus, T-Cell Receptor CRISPR, |
| Application: | Transient knock-down, stable knock-out cell generation |
| Species reactivity: | human |
1,248.00€
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CD47 CRISPR/Cas9 Lentivirus (Integrating)
Item number: BPS-78056
CD47 (also known as Rh-associated protein, GP42, Integrin-Associated Protein (IAP), or Neurophilin) is an immunoglobulin-like protein that interacts with its receptor, Signal-regulatory protein alpha (SIRPalpha), on macrophages. This binding interaction regulates transmigration, oxidative burst cytokine production,...
| Keywords: | Rh-associated protein CRISPR, GP42 lentivirus, Integrin-Associated Protein (IAP) CRISPR, Neurophilin lentivirus, |
| Application: | Transient knock-down, stable knock-out cell generation |
| Species reactivity: | human |
1,248.00€
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PD-L1 CRISPR/Cas9 Lentivirus (Integrating)
Item number: BPS-78057
The binding of Programmed Cell Death Protein 1 (PD-1), a receptor expressed on activated T-cells, to its ligands, PD-L1 and PD-L2, negatively regulates immune responses. The PD-1 ligands are found on most cancers, and the PD-1:PD-L1/2 interaction inhibits T-cell activity and allows cancer cells to escape immune...
| Keywords: | Programmed Cell Death Protein 1 CRISPR, PD-1 lentivirus, |
| Application: | Transient knock-down, stable knock-out cell generation |
| Species reactivity: | human |
1,248.00€
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TIGIT CRISPR/Cas9 Lentivirus (Integrating)
Item number: BPS-78058
TIGIT (T-cell immunoreceptor with Ig and ITIM domains, VSTM3, VSIG9) is a co-inhibitory receptor that is highly expressed in Natural Killer (NK) cells and activated CD4+, CD8+, and regulatory T-cells. Interaction with the Poliovirus Receptor (PVR, CD155) on antigen presenting cells, such as dendritic cells, recruits...
| Keywords: | VSTM3 lentivirus, VSIG9 CRISPR, |
| Application: | Transient knock-down, stable knock-out cell generation |
| Species reactivity: | human |
1,248.00€
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