Nucleic Acids

Nucleic acids, i.e. DNA and RNA directly isolated from certain organisms or organs, can be used in a variety of different experimental settings. Total RNA isolates from different tissues in combination with qPCR or Next Generation Sequencing allow a quantitative and qualitative examination of the gene expression levels in the respective tissue. Additionally this category includes the RNA genomes of phages as well as salmon sperm and calf thymus DNA.

Nucleic acids, i.e. DNA and RNA directly isolated from certain organisms or organs, can be used in a variety of different experimental settings. Total RNA isolates from different tissues in... read more »
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Nucleic Acids

Nucleic acids, i.e. DNA and RNA directly isolated from certain organisms or organs, can be used in a variety of different experimental settings. Total RNA isolates from different tissues in combination with qPCR or Next Generation Sequencing allow a quantitative and qualitative examination of the gene expression levels in the respective tissue. Additionally this category includes the RNA genomes of phages as well as salmon sperm and calf thymus DNA.

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Firefly Luciferase circRNA
Firefly Luciferase circRNA

Item number: Cay45064-1

Firefly luciferase (FLuc) circular RNA (circRNA) encodes firefly luciferase, a protein originally isolated from the firefly P. pyralis, that catalyzes the ATP-dependent oxidation of the molecule luciferin (D-luciferin, Cay25836, Cay14682, Cay14681) resulting in chemiluminescence at a wavelength of approximately 560...
Keywords: FLuc Circular RNA
Application: Sustained firefly luciferase expression
From 499.00€ *
Review
Firefly Luciferase saRNA (Cap-1)
Firefly Luciferase saRNA (Cap-1)

Item number: Cay45066-1

Firefly luciferase (FLuc) self-amplifying RNA (saRNA) (Cap-1) encodes firefly luciferase, a protein originally isolated from the firefly P. pyralis, that catalyzes the ATP-dependent oxidation of the molecule luciferin (D-luciferin, Cay25836, Cay14682, Cay14681) resulting in chemiluminescence at a wavelength of...
Keywords: FLuc Self-amplifying RNA
Application: Firefly luciferase expression
From 402.00€ *
Review
mCherry circRNA
mCherry circRNA

Item number: Cay45904-1

mCherry circular RNA (circRNA) encodes mCherry, a red fluorescent protein and derivative of Discosoma red fluorescent protein (DsRed) that displays excitation/emission maxima of 587/610 nm, respectively. Exogenous circRNAs have increased stability and can produce sustained protein expression compared to mRNA....
Keywords: mCherry Circular RNA
Application: Sustained mCherry expression
From 499.00€ *
Review
EGFP mRNA (Cap-1, m1Psi)
EGFP mRNA (Cap-1, m1Psi)

Item number: Cay45905-1

EGFP mRNA (Cap-1, m1Psi) encodes enhanced GFP (EGFP), a variant of A. Victoria GFP containing chromophore mutations that increase the sensitivity of the protein and displays excitation/emission maxima of 489/511 nm, respectively. EGFP mRNA (Cap-1, m1Psi) is polyadenylated and modified with N1-methylpseudouridine...
Keywords: Enhanced GFP mRNA
Application: eGFP expression
From 416.00€ *
Review
mCherry saRNA (Cap-1, 5mCTP)
mCherry saRNA (Cap-1, 5mCTP)

Item number: Cay45906-1

mCherry self-amplifying RNA (saRNA) (Cap-1, 5mCTP) encodes mCherry, a red fluorescent protein and derivative of Discosoma red fluorescent protein (DsRed) that displays excitation/emission maxima of 587/610 nm, respectively. It is capped with the Cap-1 structure to increase translation efficiency and modified with...
Keywords: mCherry Self-amplifying RNA
Application: mCherry expression
From 674.00€ *
Review
CpG-B DNA, Rat
CpG-B DNA, Rat

Item number: HYC-HC4040-200nmol

The rat CpG-B DNA belongs to the class of CpG-B oligodeoxynucleotides (ODN), also known as 'K'-type ODN, with a full phosphorothioate (PS) backbone. It is particularly effective for activating B cells. The vertebrate immune system has evolved innate immune defense pattern recognition receptors (PRRs) that detect...
Application: FA
Species reactivity: rat
431.00€ *
Review
CpG-DNA, Mouse
CpG-DNA, Mouse

Item number: HYC-HC4033-200nmol

Bacterial DNA is known to induce acute inflammatory responses. Bacterial DNA acts as a pathogen-associated molecular pattern by virtue of a 20-fold greater frequency of unmethylated CG dinucleotides found in microbial DNA versus vertebrate DNA. Cellular activation by deoxy-cytidylate-phosphate-deoxy-guanylate...
Application: FA
Species reactivity: mouse
431.00€ *
Review
CpG-A DNA (ODN 2216), Human/Mouse
CpG-A DNA (ODN 2216), Human/Mouse

Item number: HYC-HC4037-200nmol

ODN 2216 is a prototype of the class of CpG-A oligodeoxynucleotides (ODN), also known as 'D'-type ODN, and contains a phosphodiester (PO) backbone. It is particularly effective for activating NK cells and inducing IFN-alpha production in plasmacytoid dendritic cell (PDC) precursors. The vertebrate immune system has...
Application: FA
431.00€ *
Review
CpG-B DNA, Rabbit
CpG-B DNA, Rabbit

Item number: HYC-HC4038-200nmol

ODN 2007 is a prototype of CpG oligodeoxynucleotides (ODN) that is able to stimulate rabbit PBMC in vitro. The vertebrate immune system has evolved innate immune defense pattern recognition receptors (PRRs) that detect unmethylated cytosine-phosphate-guanine (CpG) motifs within bacterial DNA. Cellular activation by...
Species reactivity: rabbit
431.00€ *
Review
Non CpG-DNA, Human/Mouse
Non CpG-DNA, Human/Mouse

Item number: HYC-HC4034-200nmol

The vertebrate immune system has evolved innate immune defense pattern recognition receptors (PRRs) that detect unmethylated cytosine-phosphate-guanine (CpG) motifs within bacterial DNA. Cellular activation by CpG motifs occurs via the Toll signal pathway. The Toll-like receptor-9 (TLR9, CD289) appears to be a major...
431.00€ *
Review
CpG-B DNA (ODN 2006), Human/ Mouse
CpG-B DNA (ODN 2006), Human/ Mouse

Item number: HYC-HC4039-200nmol

ODN 2006 is a prototype of the class of CpG-B oligodeoxynucleotides (ODN), also known as 'K'-type ODN, with a full phosphorothioate (PS) backbone. It is particularly effective for activating B cells. The vertebrate immune system has evolved innate immune defense pattern recognition receptors (PRRs) that detect...
Application: FA
431.00€ *
Review
CpG-C DNA (ODN 2395), Human/ Mouse
CpG-C DNA (ODN 2395), Human/ Mouse

Item number: HYC-HC4041-200nmol

ODN 2395 is a prototype of the class of CpG-C oligodeoxynucleotides (ODN) and is particularly effective at activating B- and NK cells and inducing IFN-alpha production in vitro of human peripheral blood mononuclear cells (PBMC). The vertebrate immune system has evolved innate immune defense pattern recognition...
431.00€ *
Review
56 from 75 pages