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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| GSC-M00917 | 2 vials | - |
Request delivery time estimate |
11,424.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Claudins are a family of proteins, which play a role in maintaining tight cell junctions.... more
Product information "HEK293/CLDN18.2 Stable Cell Line"
Claudins are a family of proteins, which play a role in maintaining tight cell junctions. Differentclaudin subtypes are expressed on different tissues.Claudin18 isoform 2 (CLDN18.2) expressionin normal tissues is restricted to cells of the gastric mucosa and is absent from other healthytissues However, CLDN 18.2 is expressed in 70% of primary gastric adenocarcinomas and itsmetastases (101). It has also beenshown to be expressed in a number of other cancers,including pancreatic (50%), esophagus (30%) and NSCLC (25%)The restricted expressionmakes it a potential drug target for the treatment of gastric and pancreatic adenocarcinoma, asevidenced by effortsto target CLDN18.2 via naked antibody and CAR-T modalities.
| Keywords: | CLDN18, Claudin-18 |
| Supplier: | GenScript |
| Supplier-Nr: | M00917 |
Properties
Database Information
| KEGG ID : | K06087 | Matching products |
| UniProt ID : | P56856 | Matching products |
| Gene ID : | GeneID 51208 | Matching products |
Handling & Safety
| Storage: | -80°C |
| Shipping: | -80°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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