GITR / NF-kappaB-Luciferase Reporter (Luc) - Jurkat Cell Line

Item number Size Datasheet Manual SDS Delivery time Quantity Price
BPS-60546 2 vials - -

3 - 15 business days*

12,574.00€
 
This cell line expresses a surface human GITR (glucocorticoid-induced TNFR family related gene,... more
Product information "GITR / NF-kappaB-Luciferase Reporter (Luc) - Jurkat Cell Line"
This cell line expresses a surface human GITR (glucocorticoid-induced TNFR family related gene, TNFRSF18, CD357) and an NF-kappaB luciferase reporter construct that are stably integrated into the genome of Jurkat T-cells. The firefly luciferase gene is controlled by 4 copies of NF-kappaB response element located upstream of the TATA promoter. Following activation by stimulants, endogenous NF-kappaB transcription factors bind to the DNA response elements to induce transcription of the luciferase gene. The cells have been validated using purified human GITRL and anti-GITR neutralizing antibody.
Keywords: AITR, CD357, TNFRSF18, Activation-inducible TNFR family receptor, Glucocorticoid-induced TNFR-related protein, Tumor necrosis factor receptor superfamily member 18
Supplier: BPS Bioscience
Supplier-Nr: 60546

Properties

Application: NF-kB signaling activity monitoring, GITRL response
Species reactivity: human

Handling & Safety

Storage: Liquid nitrogen (store in liquid nitrogen)
Shipping: -80°C (International: -80°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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