Dual Epitope Anti-BCMA CAR-T Cells

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
BPS-78790-1	1 vial		-	-	3 - 8 business days*		2,313.00€
BPS-78790-2	5 vials		-	-	3 - 8 business days*		5,980.00€

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The Dual Epitope Anti-BCMA CAR-T Cells are generated via high-titer lentiviral transduction of... more

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Product information "Dual Epitope Anti-BCMA CAR-T Cells"

The Dual Epitope Anti-BCMA CAR-T Cells are generated via high-titer lentiviral transduction of human primary CD4+ and CD8+ T cells with the SIN Anti-BCMA CAR Lentivirus (VHH1/VHH2 ScFv-CD8-4-1BB-CD3zeta) (#78783). These ready-to use CAR (chimeric antigen receptor)-T cells express an anti-BCMA CAR consisting of a ScFv (single-chain variable fragment) that recognizes two BCMA epitopes (VHH1 and VHH2) linked to a CD8 hinge and transmembrane domains, and the 4-1BB and CD3zeta signaling domains. These CAR-T cells have been validated by flow cytometry (to determine the CAR expression) and in co-culture cytotoxicity assays.

Keywords:	BCM, CD269, TNFRSF17, B-cell maturation protein, Tumor necrosis factor receptor superfamily member 17,
Supplier:	BPS Bioscience
Supplier-Nr:	78790

Properties

Application:	Positive control, modulator screening, co-culture cytotoxicity assay design/optimization
Species reactivity:	human

Database Information

KEGG ID :	K05153 \| Matching products
UniProt ID :	Q02223 \| Matching products
Gene ID :	GeneID 608 \| Matching products

Handling & Safety

Storage:	Liquid nitrogen
Shipping:	-80°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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