CFTR - HEK293 recombinant human stable cell line (2x10(6) cells)

The CFTR-HEK293 Cell Line expresses full length, human cystic fibrosis transmembrane conductance regulator (CFTR) protein (Genbank # P13569). The expression of CFTR is confirmed by Western blotting. A synthetic codon-optimized DNA sequence encoding human CFTR protein [2] with C-terminal Streptavidin-Binding Peptide (SBP) [3] tag is stably integrated in 293HEK-Trex cells. Application: Drug compound screening, Functional Assays, Efficient antigen for mouse immunization. References: 1. Gadsby, D.C., et al. Nature 440 (7083): 477-483 (2006). 2. Hillier, L.W., et al. Nature 424:157-164 (2003). 3. McCann, C. M., et al. BioTechniques 38 (6):945-952 (2005).