Anti-CD19/CD20 CAR-T Cells

Anti-CD19/CD20 CAR-T Cells
Item number Size Datasheet Manual SDS Delivery time Quantity Price
BPS-82481 1 vial - -

3 - 8 business days*

2,992.00€
 
Anti-CD19/CD20 CAR-T Cells are produced by high-titer lentiviral transduction of human primary... more
Product information "Anti-CD19/CD20 CAR-T Cells"
Anti-CD19/CD20 CAR-T Cells are produced by high-titer lentiviral transduction of human primary CD4+ and CD8+ T cells using Anti-CD19/CD20 CAR Lentivirus. These ready-to-use CAR (chimeric antigen receptor)-T cells express an anti-CD19/CD20 CAR consisting of the ScFv portions of both anti-CD20 (Clone OMB-157) and anti-CD19 (clone FMC63) linked to a second generation CAR containing IgG4 hinge and CD28 transmembrane domains, 4-1BB and CD3zeta signaling domains (Figure 1).These CAR-T cells have been validated using flow cytometry (to determine CAR expression) and co-culture cytotoxicity assays. Figure 1. Construct diagram showing components of the Anti-CD19/CD20 CAR expressed in Anti-CD19/CD20 CAR-T Cells.
Keywords: CD19, B-lymphocyte antigen CD19, Differentiation antigen CD19, T-cell surface antigen Leu-12, B-lymphocyte surface antigen B4,
Supplier: BPS Bioscience
Supplier-Nr: 82481

Properties

Application: CAR-T cell development positive control, modulator screening, co-culture cytotoxicity assay desig
Species reactivity: human

Handling & Safety

Storage: Liquid nitrogen
Shipping: -80°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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