Cells and Cell Lines

Cell culture and microbial culture techniques are essential for almost every aspect of biological research since modern microbiology started in the 19th century. The invention of microbial cultures of bacteria and yeast in sterile culture media allows selective growing of monoclonal cultures. From these cultures, competent cells can be generated for the use in transformation. Cell culture colloquially refers to cultures of animal cells, in which we differentiate between ex vivo cultures and immortalized cell lines. Ex vivo cultures are derived from blood or organs and have a limited life span. Immortalized cell lines, however, are usually derived from tumors and proliferate indefinitely due to mutations in the cell cycle controls.

Cell culture and microbial culture techniques are essential for almost every aspect of biological research since modern microbiology started in the 19th century. The invention of microbial... read more »
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Cells and Cell Lines

Cell culture and microbial culture techniques are essential for almost every aspect of biological research since modern microbiology started in the 19th century. The invention of microbial cultures of bacteria and yeast in sterile culture media allows selective growing of monoclonal cultures. From these cultures, competent cells can be generated for the use in transformation. Cell culture colloquially refers to cultures of animal cells, in which we differentiate between ex vivo cultures and immortalized cell lines. Ex vivo cultures are derived from blood or organs and have a limited life span. Immortalized cell lines, however, are usually derived from tumors and proliferate indefinitely due to mutations in the cell cycle controls.

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HLA-A/B/C Knockout HEK293T Cell Line
HLA-A/B/C Knockout HEK293T Cell Line

Item number: BPS-82943

The HLA-A/B/C Knockout HEK293T Cell Line is a clonal HEK293T cell line that does not express Human Leukocyte Antigen (HLA)-A, HLA-B, and HLA-C. This knockout cell line was generated by CRISPR/Cas9 genome editing using sgRNAs that target regions common to all three genes. This cell line has been validated by flow...
Keywords: HLAA, HLA-A, Human leukocyte antigen A, HLA class I histocompatibility antigen, A alpha chain,
Application: Specific HLA-A, B, or C allele expression, antigen presentation
Species reactivity: human
9,955.00€ *
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216 from 216 pages