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PD-1 Lentivirus
Item number: BPS-82348
The PD-1 Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. These viruses transduce cells with human PD-1 (Programmed Death Protein 1) (NM_005018.3) driven by a CMV promoter. The...
| Keywords: | PD-1, PD1, Programmed Death 1, |
| Application: | Human PD-1 expression in cells of interest, cell pool/stable cell line (Blasticidin selection) |
1,417.00€
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Estrogen Luciferase Reporter T47D Cell Line
Item number: BPS-82349
Estrogen Luciferase Reporter T47D Cell Line is a human breast cancer, ERalpha (estrogen receptor alpha)-positive luminal A cell line, with a stably integrated Firefly luciferase reporter under the control of an estrogen response element (ERE). This cell line monitors the activity of the ER signaling pathway. This...
| Keywords: | Estrogen receptor, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1, ESR1, ESR, NR3A1, |
| Application: | Modulator screening/characterization, otential drug candidate evaluation (ER-directed therapies) |
3,959.00€
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NF-kappaB Luciferase-eGFP Reporter HEK293 Cell Line
Item number: BPS-82389
NF-kappaB Luciferase-eGFP Reporter HEK293 Cell Line is a HEK293 cell line designed to monitor nuclear factor Kappa B (NF-kappaB) activity. It contains a firefly luciferase-eGFP (enhanced green fluorescent protein) reporter driven by multiple copies of the NF-kappaB response element located upstream of the minimal...
| Keywords: | NF-kB reporter, NFkappaB reporter, NFkB, nfkb, nf-kb, |
| Application: | NF-kappaB activity monitoring, NF-kappaB signaling pathway agent screeninng/characterization |
2,569.00€
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MAGE-A4 TCR-T Cells
Item number: BPS-82390
The MAGE-A4 TCR-T Cells are generated by high-titer lentiviral transduction of human primary CD4+ and CD8+ T cells with MAGE-A4-Specific TCR Lentivirus (#78935). These ready-to-use TCR (T cell receptor)-T cells express the human TCR that specifically recognizes antigen MAGE-A4 (Melanoma-associated antigen 4). These...
| Keywords: | MAGEA4, Melanoma-associated antigen 4, Cancer/testis antigen 1.4 (CT1.4), MAGE-4 antigen, MAGE-41 antigen, MAGE-X2... |
| Application: | Positive control, MAGE-A4 TCR-T cell-driven cytotoxicity modulator screening |
2,710.00€
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PRAME TCR-T cells
Item number: BPS-82391
The PRAME TCR-T Cells are generated by high-titer lentiviral transduction of human primary CD4+ and CD8+ T cells with PRAME-Specific TCR Lentivirus (#78959). These ready-to-use TCR (T cell receptor)-T cells express the human TCR that specifically recognizes antigen PRAME (Preferentially Expressed Antigen in...
| Keywords: | Opa-interacting protein 4, OIP-4 1, publication Preferentially expressed antigen of melanoma, MAPE, |
| Application: | Positive control, PRAME TCR-T cell-driven cytotoxicity modulator screening |
2,710.00€
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Untransduced T Cells (MAGE-A4 TCR-T Negative Control)
Item number: BPS-82396
The Untransduced T Cells (MAGE-A4 TCR-T Negative Control) were produced by mock lentiviral transduction of human primary CD4+ and CD8+ T cells. These cells are subjected to comparable manipulations as TCR (T cell receptor)-T cells: activation, spinoculation (without lentivirus), and antigen specific stimulation....
| Keywords: | MAGEA4, Melanoma-associated antigen 4, Cancer/testis antigen 1.4 (CT1.4), MAGE-4 antigen, MAGE-41 antigen, MAGE-X2... |
| Application: | Negative control (lentivirus-transduced TCR-T cells expressing MAGE-A4) |
1,417.00€
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Untransduced T Cells (PRAME TCR-T Negative Control)
Item number: BPS-82397
The Untransduced T Cells (PRAME TCR-T Negative Control) were produced by mock lentiviral transduction of human primary CD4+ and CD8+ T cells. These cells are subjected to comparable manipulations as TCR (T cell receptor)-T cells: activation, spinoculation (without lentivirus), and antigen specific stimulation. These...
| Keywords: | PRAME, MAPE. OIP4, Opa-interacting protein 4, Preferentially expressed antigen of melanoma,, |
| Application: | Negative control (lentivirus-transduced PRAME TCR-T cells) |
1,417.00€
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Muscarinic Acetylcholine Receptor (mAChR) M1/NFAT...
Item number: BPS-82727
The Muscarinic Acetylcholine Receptor (mAChR) M1/NFAT Luciferase Reporter HEK293 Cell Line is a HEK293 cell line stably expressing the full-length human muscarinic acetylcholine receptor M1 (CHRM1/M1R/M1, accession number: AF498915) and a firefly luciferase reporter under the control of NFAT (nuclear factor of...
| Keywords: | Muscarinic acetylcholine receptor M1, CHRM1, M1R, NFAT, |
| Application: | Activator/inhibitor screening, drug discovery |
| Host: | Human cells |
9,897.00€
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Muscarinic Acetylcholine Receptor (mAChR) M3 /NFAT...
Item number: BPS-82728
The Muscarinic Acetylcholine Receptor (mAChR) M3/NFAT Luciferase Reporter HEK293 Cell Line is a HEK293 cell line expressing the full-length human muscarinic acetylcholine receptor M3 (CHRM3/M3R/M3, accession number: NM_000740.3) and a firefly luciferase reporter under the control of the NFAT (nuclear factor of...
| Keywords: | Muscarinic acetylcholine receptor M3, CHRM3, |
| Application: | Activator/inhibitor screening, drug discovery |
9,897.00€
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IL-5 Responsive Luciferase Reporter Ba/F3 Cell Line
Item number: BPS-82731
The IL-5 Responsive Luciferase Reporter Ba/F3 Cell Line is a murine Ba/F3 cell line engineered to express both human IL-5RA (IL-5 receptor alpha, also known as CD125) (NM_175726.4) and human CSF2RB (common receptor beta chain also known as IL5RB or CD131) (NM_000395.3), separated by a self-cleaving P2A peptide. The...
| Keywords: | IL-5, Interleukin-5, IL5, B-cell differentiation factor I, Eosinophil differentiation factor, T-cell replacing factor (TRF), |
| Application: | IL-5 signaling modulator screening/characterization |
10,029.00€
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STEAP1 HEK293 Cell Line
Item number: BPS-82749
STEAP1 HEK293 Cell Line is a HEK293 cell line expressing STEAP1 (six transmembrane epithelial antigen of the prostate 1, NM_012449.3) under the control of a cytomegalovirus (CMV) promoter. This cell line was generated by lentiviral transduction followed by puromycin selection and limited dilution. Individual clones...
| Keywords: | Six-transmembrane epithelial antigen of prostate 1, PRSS24, STEAP, |
| Application: | Therapeutic antibody/STEAP1 targeting ADC screening, STEAP1-directed CAR-T cell co-culture assays |
4,768.00€
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Firefly Luciferase A375 Cell line
Item number: BPS-82789
Firefly Luciferase A375 Cell Line is an A375 human melanoma cell line engineered to express Firefly luciferase driven by a CMV promoter. This cell line was generated by transduction with Firefly Luciferase Lentivirus (#79692-P).
| Keywords: | CDX Models, A375, |
| Application: | Internal co-culture killing assay control, in vitro/in vivo bioluminescence imaging |
1,781.00€
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