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CpG-B DNA, Rat
Item number: HYC-HC4040-200nmol
The rat CpG-B DNA belongs to the class of CpG-B oligodeoxynucleotides (ODN), also known as 'K'-type ODN, with a full phosphorothioate (PS) backbone. It is particularly effective for activating B cells. The vertebrate immune system has evolved innate immune defense pattern recognition receptors (PRRs) that detect...
| Application: | FA |
| Species reactivity: | rat |
431.00€
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CpG-DNA, Mouse
Item number: HYC-HC4033-200nmol
Bacterial DNA is known to induce acute inflammatory responses. Bacterial DNA acts as a pathogen-associated molecular pattern by virtue of a 20-fold greater frequency of unmethylated CG dinucleotides found in microbial DNA versus vertebrate DNA. Cellular activation by deoxy-cytidylate-phosphate-deoxy-guanylate...
| Application: | FA |
| Species reactivity: | mouse |
431.00€
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CpG-A DNA (ODN 2216), Human/Mouse
Item number: HYC-HC4037-200nmol
ODN 2216 is a prototype of the class of CpG-A oligodeoxynucleotides (ODN), also known as 'D'-type ODN, and contains a phosphodiester (PO) backbone. It is particularly effective for activating NK cells and inducing IFN-alpha production in plasmacytoid dendritic cell (PDC) precursors. The vertebrate immune system has...
| Application: | FA |
431.00€
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CpG-B DNA, Rabbit
Item number: HYC-HC4038-200nmol
ODN 2007 is a prototype of CpG oligodeoxynucleotides (ODN) that is able to stimulate rabbit PBMC in vitro. The vertebrate immune system has evolved innate immune defense pattern recognition receptors (PRRs) that detect unmethylated cytosine-phosphate-guanine (CpG) motifs within bacterial DNA. Cellular activation by...
| Species reactivity: | rabbit |
431.00€
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Non CpG-DNA, Human/Mouse
Item number: HYC-HC4034-200nmol
The vertebrate immune system has evolved innate immune defense pattern recognition receptors (PRRs) that detect unmethylated cytosine-phosphate-guanine (CpG) motifs within bacterial DNA. Cellular activation by CpG motifs occurs via the Toll signal pathway. The Toll-like receptor-9 (TLR9, CD289) appears to be a major...
431.00€
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CpG-B DNA (ODN 2006), Human/ Mouse
Item number: HYC-HC4039-200nmol
ODN 2006 is a prototype of the class of CpG-B oligodeoxynucleotides (ODN), also known as 'K'-type ODN, with a full phosphorothioate (PS) backbone. It is particularly effective for activating B cells. The vertebrate immune system has evolved innate immune defense pattern recognition receptors (PRRs) that detect...
| Application: | FA |
431.00€
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CpG-C DNA (ODN 2395), Human/ Mouse
Item number: HYC-HC4041-200nmol
ODN 2395 is a prototype of the class of CpG-C oligodeoxynucleotides (ODN) and is particularly effective at activating B- and NK cells and inducing IFN-alpha production in vitro of human peripheral blood mononuclear cells (PBMC). The vertebrate immune system has evolved innate immune defense pattern recognition...
431.00€
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TLR9, Mouse, antagonist (ODN2088)
Item number: HYC-HC4074-1MG
Dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions.
| Keywords: | Toll-like receptor 9, CD289 Gene name: Tlr9 |
| Application: | FA |
| Species reactivity: | mouse |
From 190.00€
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NEW
TruCytes(TM) Potency CD19 Evaluation Kit
Item number: SLI-SL-00035
Available in limited quantities, our TruCytes Potency CD19 Evaluation kit is for CAR-T developers to assess functional potency using Slingshot's precision-engineered TruCytes Potency CD19 cell mimics. Each kit supports assay development and optimization with targeted activation, consistent cytokine release, and full...
| Application: | Cell mimics, FC |
| Host: | Synthetic cells |
1,369.00€
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NEW
TruCytes(TM) Potency BCMA Evaluation Kit
Item number: SLI-SL-00036
Available in limited quantities, our TruCytes Potency BCMA Evaluation kit is for CAR-T developers to assess functional potency using Slingshot's precision-engineered TruCytes Potency BCMA cell mimics. Each kit supports assay development and optimization with targeted activation, consistent cytokine release, and full...
| Application: | Cell mimics, FC |
| Host: | Synthetic cells |
1,369.00€
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NEW
TruCytes(TM) Potency CD20 Evaluation Kit
Item number: SLI-SL-00043
TruCytes Potency CD20 Evaluation kit is for CAR-T developers to assess functional potency using Slingshot's precision-engineered TruCytes Potency CD20 cell mimics. Each kit supports assay development and optimization with targeted activation, consistent cytokine release, and full technical support. Kit Components:...
| Application: | Cell mimics, FC |
| Host: | Synthetic cells |
910.00€
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Firefly Luciferase CD22 Knockout Raji Cell Line
Item number: BPS-82971
Firefly Luciferase CD22 Knockout Raji Cell Line is a Raji cell line in which CD22 (Cluster of Differentiation 22, or SIGLEC2) is not expressed due to CRISPR/Cas9 genome editing. These cells also constitutively express firefly (Photinus pyralis) luciferase under the control of an EF1a promoter. This cell line was...
| Keywords: | CD22, B-cell receptor CD22, B-lymphocyte cell adhesion molecule, Sialic acid-binding Ig-like lectin 2, T-cell surface... |
| Application: | CAR-T/NK co-culture killing assay control, in vitro/in vivo bioluminescence imaging |
| Host: | Human cells |
| Species reactivity: | human |
9,897.00€
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