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Anti-GPC3 CAR-T Cells
Item number: BPS-82492
Anti-GPC3 CAR-T Cells are produced by high-titer lentiviral transduction of human primary CD4+ and CD8+ T cells using Anti-GPC3 CAR Lentivirus (Clone GC33-CD28TM-41BB-CD3zeta) (BPS Bioscience #82494). These ready-to-use CAR-T cells express an anti-GPC3 (glypican-3) CAR (chimeric antigen receptor) consisting of the...
| Keywords: | GPC3, OCI5, |
| Application: | Positive control, modulator screening, co-culture cytotoxicity assay design/optimization |
| Species reactivity: | human |
2,569.00€
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Firefly Luciferase A549 Cell Line
Item number: BPS-82495
Firefly Luciferase A549 Cell Line is a lung cancer A549 cell line that expresses the firefly luciferase reporter driven by an EF1a promoter. This cell line has been generated by transduction with Firefly Luciferase Lentivirus (BPS Bioscience #78740-H). This cell line has been validated in co-culture assays.
| Keywords: | Luciferase, Luciferin 4-monooxygenase, |
| Application: | CAR-T / NK co-culture killing assay target cells, in vitro/in vivo bioluminescence imaging |
| Species reactivity: | common eastern firefly |
1,997.00€
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HER2 Knockout MCF7 Cell Line
Item number: BPS-82857
HER2 Knockout MCF7 Cell Line is an MCF7 cell line in which human HER2 (Receptor tyrosine-protein kinase ErbB-2) has been genetically removed using CRISPR/Cas9 genome editing with a lentivirus encoding the CRISPR/Cas9 gene and sgRNA (single guide RNA) targeting human HER2. This cell line has been validated by...
| Keywords: | HER2, ERBB2, CD340, MLN 19, p185erbB2, EC=2.7.10.1, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Metastatic lymph node... |
| Application: | HER2 knockout impact studies, anti-HER2 CAR-T killing assay development control |
| Species reactivity: | human |
7,213.00€
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B2M Knockout Raji Cell Line
Item number: BPS-82870
B2M Knockout Raji Cell Line is a Raji cell line where B2M (Beta-2-Microglobulin) has been genetically removed by CRISPR/Cas9 genome editing. This cell line has been validated by sequencing and flow cytometry.
| Keywords: | CDABP0092, |
| Application: | B2M knockdown impact studies, T cell activation studies, antigen presentation, immune response studies |
| Species reactivity: | human |
9,144.00€
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CD38 Knockout A549 Cell Line
Item number: BPS-82953
CD38 Knockout A549 Cell Line is a A549 lung cancer cell line in which human CD38 (Cluster of Differentiation 38) has been genetically removed using CRISPR/Cas9 genome editing with a lentivirus encoding the CRISPR/Cas9 gene and sgRNA (single guide RNA) targeting human CD38.
| Keywords: | T10, CD38, ADPRC 1, cADPR hydrolase 1, ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1, 2'-phospho-ADP-ribosyl... |
| Application: | Negative control, CD38 knockout phenotype studies |
| Species reactivity: | human |
7,213.00€
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IL-11 Responsive Luciferase Reporter HEK293 Line
Item number: BPS-83014
The IL-11 (Interleukin-11) Responsive Luciferase Reporter HEK293 Line is a HEK293 cell line engineered to express both human IL-11Ra (IL-11 receptor alpha) (NM_001142784.3) and human IL-6ST (IL-6 cytokine family signal transducer, also known as gp130) (NM_002184.4) separated by a self-cleaving P2A peptide. The...
| Keywords: | AGIF, IL-11, Oprelvekin, Interleukin-11, Adipogenesis inhibitory factor, |
| Application: | Modulator screening |
| Species reactivity: | human |
15,164.00€
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EGFR Knockout A549 Cell Line
Item number: BPS-83541
EGFR Knockout A549 Cell line is an A549 lung cancer cell line in which human EGFR (epidermal growth factor receptor) is no longer expressed due to CRISPR/Cas9 genome editing. This cell line was generated by electroporation of A549 cells with ribonucleoprotein complexes of Cas9 and sgRNAs targeting human EGFR. This...
| Keywords: | ERBB, EC=2.7.10.1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, Receptor tyrosine-protein kinase erbB-1, |
| Application: | Negative control , EGFR knockout phenotype studies |
| Species reactivity: | human |
5,624.00€
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