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NEW
PSMA (FOLH1) Luciferase CHO Cell Line
Item number: BPS-84145
PSMA (FOLH1) Luciferase CHO Cell Line is a clonal CHO cell line stably expressing both full length human PSMA protein (NM_004476.1) and firefly luciferase. Prostate-specific membrane antigen (PSMA), also known as Folate hydrolase 1 (FOLH1), is expressed at high levels on prostate cancer cells. It has been reported...
| Keywords: | FOLH1, Glutamate carboxypeptidase 2, Cell growth-inhibiting gene 27 protein, Folate hydrolase 1, Folylpoly-gamma-glutamate... |
| Application: | Anti-PSMA bispecific antibody screening/validation, anti-PSMA CAR cell screening/validation |
| Host: | Hamster cells |
| Species reactivity: | human |
12,111.00€
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NEW
NFAT Luciferase Reporter RAW264.7 Cell Line
Item number: BPS-84147
The NFAT Luciferase Reporter RAW 264.7 Cell Line is a murine cell line that expresses the stably integrated firefly luciferase reporter under the transcriptional control of NFAT (Nuclear Factor of Activated T-cells)-responsive elements. This cell line has been validated to respond to mouse RANKL, Calcimycin (A23187)...
| Keywords: | Tnfsf11, Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor, Osteoprotegerin ligand,... |
| Application: | NFAT signaling activity monitoring, NFAT pathway targeting activator/inhibitor screening |
| Host: | Mouse cells |
| Species reactivity: | mouse |
2,569.00€
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NEW
AP1 Luciferase Reporter RAW264.7 Cell Line
Item number: BPS-84151
The AP1 Luciferase Reporter RAW 264.7 Cell Line is a murine RAW 264.7 cell line that expresses the stably integrated firefly luciferase reporter under the transcriptional control of AP1 (activator protein-1)-responsive elements. This cell line has been validated to respond to mouse RANKL and PMA. It was also tested...
| Keywords: | Ap1m1, AP-1 complex subunit mu-1, AP-mu chain family member mu1A, Adaptor protein complex AP-1 subunit mu-1,... |
| Application: | AP1 signaling activity monitoring, AP1 activation targeting activator/inhibitor screening |
| Host: | Mouse cells |
| Species reactivity: | human |
5,948.00€
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NEW
BAFF Responsive BAFF-R NF-kB Luciferase Reporter HEK293...
Item number: BPS-84178
The BAFF Responsive BAFF-R NF-kB Luciferase Reporter HEK293 Cell Line is a HEK293 cell line engineered to express a version of BAFFR (B-cell activating factor receptor, also known as TNFRSF13C, NM_052945.4] that is designed to couple with the canonical NF-kB (nuclear factor Kappa B) signaling pathway. The cells also...
| Keywords: | TNFRSF13C, Tumor necrosis factor receptor superfamily member 13C, B-cell-activating factor receptor, BAFF receptor, BLyS... |
| Application: | BAFF Receptor-targeting antibody screening, BAFF ligand-neutralizing therapy screening |
| Host: | Human cells |
| Species reactivity: | human |
16,117.00€
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Human Placental Tissue (Normal) - FFPE Block
Item number: Cay45048-1
An FFPE block containing normal human placenta tissue for IHC, 10% NBF-fixed for 24 hours and embedded in IHC-grade paraffin, target FFPE size is 1-2 x 1-2 x 0.5, but this may vary significantly based on the size of the tissue sample, can be used for IHC applications
| Keywords: | Human Placental Tissue (Normal) - Formalin-Fixed, Paraffin-Embedded Block |
| Application: | FFPE block, IHC |
| Host: | Human |
694.00€
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CpG-B DNA, Rat
Item number: HYC-HC4040-200nmol
The rat CpG-B DNA belongs to the class of CpG-B oligodeoxynucleotides (ODN), also known as 'K'-type ODN, with a full phosphorothioate (PS) backbone. It is particularly effective for activating B cells. The vertebrate immune system has evolved innate immune defense pattern recognition receptors (PRRs) that detect...
| Application: | FA |
| Species reactivity: | rat |
431.00€
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CpG-DNA, Mouse
Item number: HYC-HC4033-200nmol
Bacterial DNA is known to induce acute inflammatory responses. Bacterial DNA acts as a pathogen-associated molecular pattern by virtue of a 20-fold greater frequency of unmethylated CG dinucleotides found in microbial DNA versus vertebrate DNA. Cellular activation by deoxy-cytidylate-phosphate-deoxy-guanylate...
| Application: | FA |
| Species reactivity: | mouse |
431.00€
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CpG-A DNA (ODN 2216), Human/Mouse
Item number: HYC-HC4037-200nmol
ODN 2216 is a prototype of the class of CpG-A oligodeoxynucleotides (ODN), also known as 'D'-type ODN, and contains a phosphodiester (PO) backbone. It is particularly effective for activating NK cells and inducing IFN-alpha production in plasmacytoid dendritic cell (PDC) precursors. The vertebrate immune system has...
| Application: | FA |
431.00€
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CpG-B DNA, Rabbit
Item number: HYC-HC4038-200nmol
ODN 2007 is a prototype of CpG oligodeoxynucleotides (ODN) that is able to stimulate rabbit PBMC in vitro. The vertebrate immune system has evolved innate immune defense pattern recognition receptors (PRRs) that detect unmethylated cytosine-phosphate-guanine (CpG) motifs within bacterial DNA. Cellular activation by...
| Species reactivity: | rabbit |
431.00€
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Non CpG-DNA, Human/Mouse
Item number: HYC-HC4034-200nmol
The vertebrate immune system has evolved innate immune defense pattern recognition receptors (PRRs) that detect unmethylated cytosine-phosphate-guanine (CpG) motifs within bacterial DNA. Cellular activation by CpG motifs occurs via the Toll signal pathway. The Toll-like receptor-9 (TLR9, CD289) appears to be a major...
431.00€
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CpG-B DNA (ODN 2006), Human/ Mouse
Item number: HYC-HC4039-200nmol
ODN 2006 is a prototype of the class of CpG-B oligodeoxynucleotides (ODN), also known as 'K'-type ODN, with a full phosphorothioate (PS) backbone. It is particularly effective for activating B cells. The vertebrate immune system has evolved innate immune defense pattern recognition receptors (PRRs) that detect...
| Application: | FA |
431.00€
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CpG-C DNA (ODN 2395), Human/ Mouse
Item number: HYC-HC4041-200nmol
ODN 2395 is a prototype of the class of CpG-C oligodeoxynucleotides (ODN) and is particularly effective at activating B- and NK cells and inducing IFN-alpha production in vitro of human peripheral blood mononuclear cells (PBMC). The vertebrate immune system has evolved innate immune defense pattern recognition...
431.00€
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