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CpG-DNA, Mouse
Item number: HYC-HC4033-200nmol
Bacterial DNA is known to induce acute inflammatory responses. Bacterial DNA acts as a pathogen-associated molecular pattern by virtue of a 20-fold greater frequency of unmethylated CG dinucleotides found in microbial DNA versus vertebrate DNA. Cellular activation by deoxy-cytidylate-phosphate-deoxy-guanylate...
| Application: | FA |
| Species reactivity: | mouse |
431.00€
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CpG-A DNA (ODN 2216), Human/Mouse
Item number: HYC-HC4037-200nmol
ODN 2216 is a prototype of the class of CpG-A oligodeoxynucleotides (ODN), also known as 'D'-type ODN, and contains a phosphodiester (PO) backbone. It is particularly effective for activating NK cells and inducing IFN-alpha production in plasmacytoid dendritic cell (PDC) precursors. The vertebrate immune system has...
| Application: | FA |
431.00€
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CpG-B DNA, Rabbit
Item number: HYC-HC4038-200nmol
ODN 2007 is a prototype of CpG oligodeoxynucleotides (ODN) that is able to stimulate rabbit PBMC in vitro. The vertebrate immune system has evolved innate immune defense pattern recognition receptors (PRRs) that detect unmethylated cytosine-phosphate-guanine (CpG) motifs within bacterial DNA. Cellular activation by...
| Species reactivity: | rabbit |
431.00€
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CpG-B DNA, Rat
Item number: HYC-HC4040-200nmol
The rat CpG-B DNA belongs to the class of CpG-B oligodeoxynucleotides (ODN), also known as 'K'-type ODN, with a full phosphorothioate (PS) backbone. It is particularly effective for activating B cells. The vertebrate immune system has evolved innate immune defense pattern recognition receptors (PRRs) that detect...
| Application: | FA |
| Species reactivity: | rat |
431.00€
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Non CpG-DNA, Human/Mouse
Item number: HYC-HC4034-200nmol
The vertebrate immune system has evolved innate immune defense pattern recognition receptors (PRRs) that detect unmethylated cytosine-phosphate-guanine (CpG) motifs within bacterial DNA. Cellular activation by CpG motifs occurs via the Toll signal pathway. The Toll-like receptor-9 (TLR9, CD289) appears to be a major...
431.00€
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CpG-B DNA (ODN 2006), Human/ Mouse
Item number: HYC-HC4039-200nmol
ODN 2006 is a prototype of the class of CpG-B oligodeoxynucleotides (ODN), also known as 'K'-type ODN, with a full phosphorothioate (PS) backbone. It is particularly effective for activating B cells. The vertebrate immune system has evolved innate immune defense pattern recognition receptors (PRRs) that detect...
| Application: | FA |
431.00€
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CpG-C DNA (ODN 2395), Human/ Mouse
Item number: HYC-HC4041-200nmol
ODN 2395 is a prototype of the class of CpG-C oligodeoxynucleotides (ODN) and is particularly effective at activating B- and NK cells and inducing IFN-alpha production in vitro of human peripheral blood mononuclear cells (PBMC). The vertebrate immune system has evolved innate immune defense pattern recognition...
431.00€
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TLR9, Mouse, antagonist (ODN2088)
Item number: HYC-HC4074-1MG
Dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions.
| Keywords: | Toll-like receptor 9, CD289 Gene name: Tlr9 |
| Application: | FA |
| Species reactivity: | mouse |
From 190.00€
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Membrane KLK2 CHO Cell Line
Item number: BPS-83060
Membrane KLK2 CHO Cell Line is a clonal CHO cell line stably expressing membrane human KLK2 (kallikrein 2) (NM_005551.5). Surface expression of KLK2 was confirmed by flow cytometry. This cell line was functionally validated in a co-culture assay with Pasritamig (anti-KLK2, anti-CD3 bispecific antibody) by activation...
| Keywords: | KLK2, Kallikrein-2, Glandular kallikrein-1, Tissue kallikrein-2 |
| Application: | Antibody screening/validation, drug discovery, co-culture experiments |
| Species reactivity: | human |
5,618.00€
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DLL3 Knockout SHP-77 Cell Line
Item number: BPS-83570
DLL3 Knockout SHP-77 Cell line is a human small cell lung cancer (SCLC) cell line, in which DLL3 (Delta-like canonical Notch ligand 3) is not expressed due to CRISPR/Cas9 genome editing. This cell line was validated by flow cytometry. Small cell lung cancer (SCLC), an aggressive form of cancer, accounts for about...
| Keywords: | DLL3, Delta-like protein 3, Drosophila Delta homolog 3 |
| Application: | T cell killing assay control, ADC control |
| Species reactivity: | human |
6,269.00€
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ZsGreen Knock-in TRAC Knock-out Jurkat Cell Line
Item number: BPS-83786
ZsGreen Knock-in TRAC Knock-out Jurkat Cell Line is a Jurkat knock-in cell line that expresses ZsGreen (Zoanthus sp. green fluorescent protein) in the TRAC (T-Cell Receptor Alpha Constant) locus. As a result, the endogenous TRAC is knocked out and no longer expressed. This cell line was generated by electroporation...
| Keywords: | TRAC, T cell receptor alpha chain constant |
| Application: | CAR-T-specific cell killing control, knock-out control, knock-in studies |
| Species reactivity: | human |
12,111.00€
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Rat GLP-1R/CRE Luciferase Reporter HEK293 Cell Line
Item number: BPS-83880
Rat GLP-1R/CRE Luciferase Reporter HEK293 Cell Line is an engineered HEK293 cell line expressing firefly luciferase under the control of cAMP response element (CRE), and rat GLP-1R (Rattus norvegicus Glucagon-like peptide 1 receptor, NM_012728.2). Activation of rat GLP-1R in these cells can be monitored by measuring...
| Keywords: | Glp1r, Glucagon-like peptide 1 receptor |
| Application: | Agonist screening |
| Species reactivity: | rat |
14,180.00€
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