Uncoated Mouse NT-proBNP (N-terminal pro-Brain Natriuretic Peptide) ELISA Kit

Type: Sandwich-ELISA. Detection Range: 15.63-1000 pg/mL. Sensitivity: . Tested Sample Types: Serum, plasma. Test principle: Protein function: [Brain natriuretic peptide 45]: Cardiac hormone that plays a key role in mediating cardio-renal homeostasis (PubMed:8182124). May also function as a paracrine antifibrotic factor in the heart (PubMed:10737768). Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses (PubMed:8182124). Likely involved in regulating the extracellular fluid volume and maintaining the fluid- electrolyte balance through natriuresis, diuresis, kaluresis and chloruresis. [The UniProt Consortium]