sCD59, Human, ELISA kit

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
HYC-HK374-01	96 tests (1 x 96 det.)	-			Request delivery time estimate		858.00€
HYC-HK374-02	192 tests (2 x 96 det.)	-			Request delivery time estimate		1,413.00€

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Protein Function: Potent inhibitor of the complement membrane attack complex (MAC) action, which... more

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Product information "sCD59, Human, ELISA kit"

Protein Function: Potent inhibitor of the complement membrane attack complex (MAC) action, which protects human cells from damage during complement activation (PubMed:11882685, PubMed:1698710, PubMed:2475111, PubMed:2475570, PubMed:2606909, PubMed:9053451). Acts by binding to the beta-haipins of C8 (C8A and C8B) components of the assembling MAC, forming an intermolecular beta-sheet that prevents incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore (PubMed:11882685, PubMed:1698710, PubMed:36797260) , The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit complement membrane attack complex (MAC) assembly on cell membranes [The Uniprot Consortium]

Keywords:	CD59, Protectin, 1F5 antigen, MEM43 antigen, CD59 glycoprotein, MAC-inhibitory protein, Membrane inhibitor of reactive lysis, 20 kDa homologous restriction factor, Membrane attack complex inhibition factor
Supplier:	Hycult Biotech
Supplier-Nr:	HK374

Properties

Application:	ELISA
Species reactivity:	human

Database Information

KEGG ID :	K04008 \| Matching products
UniProt ID :	P13987 \| Matching products
Gene ID :	GeneID 966 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+20°C (International: °C)
Signal Word:	Danger
H Phrases:	H302, H312, H318
P Phrases:	P305+P351+P338

Caution
Our products are for laboratory research use only: Not for administration to humans!

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