RBP4 (mouse/rat) Dual BioAssay(TM) ELISA Kit (Retinol Binding Protein 4)

Retinol binding protein 4 (RBP4, RBP) is a 21kD secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function and recent studies have shown an association between serum RBP4 levels and urinary albumin excretion. The urinary RBP4 concentration may be a valuable marker for both, insulin resistance and microalbuminuria in insulin-resistant subjects. Specificity: Recognizes mouse and rat RBP4. Does not cross-react with human RBP4, mouse adiponectin, mouse resistin, mouse Nampt, rat adiponectin, rat resistin or rat Nampt. Storage and Stability: Short-term Storage: +4°C, Long-term Storage: +4°C