QuicKey Pro Human PR3 (Proteinase 3) ELISA Kit
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
PRTN3,serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen... more
Product information "QuicKey Pro Human PR3 (Proteinase 3) ELISA Kit"
PRTN3,serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro. By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration. May play a role in neutrophil transendothelial migration, probably when associated with CD177.Gene AliasPRTN3Gene ID5657Uniport IDP24158Protein AliasPRTN3Research AreaSignal Transduction Protein function: Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:2033050, PubMed:28240246, PubMed:3198760). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369). Plays a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279). Triggers inflammatory processes in neutrophils by interacting with ADGRG3 upstream of F2RL1/PAR2 activation (PubMed:36302784). [The UniProt Consortium]
| Keywords: | PR3, MBN, P29, AGP7, NP-4, PR-3, PRTN3, Myeloblastin, C-ANCA antigen, Wegener autoantigen, Leukocyte proteinase 3, Neutrophil proteinase 4 |
| Supplier: | Elabscience |
| Supplier-Nr: | E-OSEL-H0054 |
Properties
| Application: | ELISA |
| Species reactivity: | human |
| Format: | Solid Phase |
Database Information
| KEGG ID : | K01350 | Matching products |
| UniProt ID : | P24158 | Matching products |
| Gene ID : | GeneID 5657 | Matching products |
Handling & Safety
| Storage: | vT |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H317 |
| P Phrases: | P261, P272, P280, P302+352, P333+313 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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