Proteinase 3, Human, ELISA kit

Proteinase 3, Human, ELISA kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
HYC-HK384-01 96 tests (1 x 96 det.) -

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858.00€
HYC-HK384-02 192 tests (2 x 96 det.) -

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1,413.00€
 
Protein Function: Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and... more
Product information "Proteinase 3, Human, ELISA kit"
Protein Function: Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:2033050, PubMed:28240246, PubMed:3198760). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369). Plays a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279). Triggers inflammatory processes in neutrophils by interacting with ADGRG3 upstream of F2RL1/PAR2 activation (PubMed:36302784) [The Uniprot Consortium]
Keywords: P29, AGP7, PRTN3, Myeloblastin, C-ANCA antigen, Wegener autoantigen, Leukocyte proteinase 3, Neutrophil proteinase 4
Supplier: Hycult Biotech
Supplier-Nr: HK384

Properties

Application: ELISA
Species reactivity: human

Handling & Safety

Storage: +4°C
Shipping: +20°C (International: °C)
Signal Word: Danger
H Phrases: H302, H312, H318
P Phrases: P305+P351+P338
Caution
Our products are for laboratory research use only: Not for administration to humans!
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