Porcine FGF1 (Heparin-binding growth factor 1) ELISA Kit

Porcine FGF1 (Heparin-binding growth factor 1) ELISA Kit is a high quality kit for research use only from Assay Genie. The Porcine FGF1 (Heparin-binding growth factor 1) ELISA Kit comes in a 96 Assays format and reacts against Porcine samples. We ship this kit on Gel Pack and kits should be stored at 2-8°C Protein Function: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrin ITGAV:ITGB3. Its binding to integrin, subsequent ternary complex formation with integrin and FGFR1, and the recruitment of PTPN11 to the complex are essential for FGF1 signaling. Induces the phosphorylation and activation of FGFR1, FRS2, MAPK3/ERK1, MAPK1/ERK2 and AKT1. Can induce angiogenesis [The Uniprot Consortium]