Mouse RUNX2 (Runt Related Transcription Factor 2) ELISA Kit

Mouse RUNX2 (Runt Related Transcription Factor 2) ELISA Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-MOES01453.96 96 assays -

9 - 20 business days*

708.00€
 
ELISA Type: Sandwich. Sensitivity: 0.188ng/mL. Range: 0.313--20ng/mL. Protein function:... more
Product information "Mouse RUNX2 (Runt Related Transcription Factor 2) ELISA Kit"
ELISA Type: Sandwich. Sensitivity: 0.188ng/mL. Range: 0.313--20ng/mL. Protein function: Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. Inhibits KAT6B-dependent transcriptional activation. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2- mediated activation of the osteocalcin FGF-responsive element (OCFRE). [The UniProt Consortium]
Keywords: Aml3, OSF-2, Runx2, CBF-alpha-1, PEA2-alpha A, PEBP2-alpha A, Oncogene AML-3, Acute myeloid leukemia 3 protein, Runt-related transcription factor 2, Core-binding factor subunit alpha-1, SL3-3 enhancer factor 1 alpha A subunit
Supplier: Assay Genie
Supplier-Nr: MOES01453

Properties

Application: Sandwich ELISA
Species reactivity: mouse
Format: Solid Phase

Handling & Safety

Storage: vT
Shipping: +4°C (International: +4°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315, H319
P Phrases: P264, P280
Caution
Our products are for laboratory research use only: Not for administration to humans!
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