Mouse Mucosal addressin cell adhesion molecule 1 (MADCAM1) ELISA kit

Detection Range: Request Information Sensitivity: Request Information Assay Principle: Measurement: Assay Time: 1-5h Sample Volume: 50-100ulDetection Wavelength: 450 nmProtein function: Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both the integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Both isoform 1 and isoform 2 can adhere to integrin alpha-4/beta-7. Isoform 2, lacking the mucin- like domain, may be specialized in supporting integrin alpha-4/beta-7- dependent adhesion strengthening, independent of L-selectin binding. [The UniProt Consortium]