Mouse CX3CL1 (Chemokine C-X3-C-Motif Ligand 1) Superset Max DIY ELISA

Mouse CX3CL1 (Chemokine C-X3-C-Motif Ligand 1) Superset Max DIY ELISA Protein Function: Chemokine that acts as a ligand for both CX3CR1 and integrins ITGAV:ITGB3 and ITGA4:ITGB1 (PubMed:10187784, PubMed:18971423). The CX3CR1-CX3CL1 signaling exerts distinct functions in different tissue compartments, such as immune response, inflammation, cell adhesion and chemotaxis (PubMed:10187784, PubMed:10382755, PubMed:18971423, PubMed:9177350). Regulates leukocyte adhesion and migration processes at the endothelium (PubMed:10382755, PubMed:9177350). Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner (By similarity). In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site (site 1) in integrins (By similarity). In the absence of CX3CR1, binds to a second site (site 2) in integrins which is distinct from site 1 and enhances the binding of other integrin ligands to site 1 (By similarity) , The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils , The membrane-bound form promotes adhesion of those leukocytes to endothelial cells [The Uniprot Consortium]