Mouse Apolipoprotein C-III (APOC3) ELISA kit

Sample Types: serum, plasma, tissue homogenates Detection Range: 18.75 ng/mL-1200 ng/mL Sensitivity: 9.375 ng/mL Assay Principle: quantitative Measurement: CompetitiveAssay Time: 1-5h Sample Volume: 50-100ulDetection Wavelength: 450 nmProtein function: Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion, extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors. Formed of several curved helices connected via semiflexible hinges, so that it can wrap tightly around the curved micelle surface and easily adapt to the different diameters of its natural binding partners. [The UniProt Consortium]