Mouse APLN (Apelin) ELISA Kit

ELISA Type: Competitive. Sensitivity: 75pg/mL. Range: 125--8000pg/mL. Protein function: Endogenous ligand for the apelin receptor (APLNR). Drives internalization of APLNR. Apelin-36 dissociates more hardly than (pyroglu)apelin-13 from APLNR. Hormone involved in the regulation of cardiac precursor cell movements during gastrulation and heart morphogenesis. Has an inhibitory effect on cytokine production in response to T-cell receptor/CD3 cross- linking, the oral intake of apelin in the colostrum and the milk might therefore modulate immune responses in neonates (PubMed:10525157). Plays a role in early coronary blood vessels formation (PubMed:28890073). Mediates myocardial contractility in an ERK1/2- dependent manner. May also have a role in the central control of body fluid homeostasis by influencing vasopressin release and drinking behavior (PubMed:11359874). [The UniProt Consortium]