IL-6 (human) ELISpot Set

Diaclone ELISpot Sets include capture and detection antibodies, Streptavidin - Alkaline Phosphatase conjugated, BSA, BCIP/NTB, blocking reagent, and no, 1, 5, 10, 15, or 20 sterile or non-sterile plates, , Cross reaction: No cross reactivity with other human cytokines. No interference with soluble receptor gp80. Incubation time: 3h after cell stimulation, , Additional info: To receive kit plus non-sterile plates (MSIPN), please add 'P' at the end of the Cat N°. To receive kit plus sterile plates (MSIPS), please add 'S' at the end of the Cat N°. Spots read visually or with reader Protein function: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans- signaling'. Alternatively, 'cluster signaling' occurs when membrane- bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable). [The UniProt Consortium]