IL-4 (rat) ELISA Set

Diaclone ELISA Sets include capture and biotinylated detection antibody, one standard per plate, Streptavidin-HRP, TMB, and detailed procedure including buffer composition., Assay Range: 31.25-1000 pg/ml, Sensitivity: 15 pg/ml, Cross reaction: No cross reactivity with other rat cytokines, Incubation time: From sample to end 4h45, Sample Types: Serum, Cell culture supernatant, Sample Size: 100 µl Protein function: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4. [The UniProt Consortium]