IL-36beta (human) Matched Pair Detection Set

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
AG-46B-0009-KI01	1 set				3 - 9 business days*		715.00€

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IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and... more

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Product information "IL-36beta (human) Matched Pair Detection Set"

IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.

Keywords:	IL36B, IL1F8, IL-1F8, IL-1H2, FIL1 eta, IL-1 eta, Interleukin-1 eta, Interleukin-36 beta, Interleukin-1 homolog 2, Interleukin-1 family member 8
Supplier:	AdipoGen Life Sciences
Supplier-Nr:	AG-46B-0009

Properties

Application:	ELISA
Species reactivity:	human
Format:	Solid Phase

Database Information

KEGG ID :	K05486 \| Matching products
UniProt ID :	Q9NZH7 \| Matching products
Gene ID :	GeneID 27177 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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