IL-17F (human) ELISpot Set

Diaclone ELISpot Sets include capture and detection antibodies, Streptavidin - Alkaline Phosphatase conjugated, BSA, BCIP/NTB, blocking reagent, and no, 1, 5, 10, 15, or 20 sterile or non-sterile plates, , Cross reaction: No cross reactivity with other human cytokines, Incubation time: 3h after cell stimulation, , Additional info: To receive kit plus non-sterile plates (MSIPN), please add 'P' at the end of the Cat N°. To receive kit plus sterile plates (MSIPS), please add 'S' at the end of the Cat N°. Spots read visually or with reader Protein function: Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in stimulating the production of other cytokines such as IL6, IL8 and CSF2, and in regulation of cartilage matrix turnover (PubMed:11591732, PubMed:11591768, PubMed:11574464). Also involved in stimulating the proliferation of peripheral blood mononuclear cells and T-cells and in inhibition of angiogenesis (PubMed:11591732). Plays a role in the induction of neutrophilia in the lungs and in the exacerbation of antigen-induced pulmonary allergic inflammation. [The UniProt Consortium]